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Gene: Ppox (protoporphyrinogen oxidase) Rattus norvegicus
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Symbol: Ppox
Name: protoporphyrinogen oxidase
Description: Exhibits oxygen-dependent protoporphyrinogen oxidase activity. Involved in heme biosynthetic process; protoporphyrinogen IX metabolic process; and response to drug. Localizes to the integral component of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in variegate porphyria. Orthologous to human PPOX (protoporphyrinogen oxidase); PARTICIPATES IN heme biosynthetic pathway; acute intermittent porphyria pathway; erythropoietic porphyria pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 3,3',4,4',5-pentachlorobiphenyl; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC289219
Orthologs:
Homo sapiens (human) : PPOX (protoporphyrinogen oxidase)  HGNC  Alliance
Mus musculus (house mouse) : Ppox (protoporphyrinogen oxidase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppox (protoporphyrinogen oxidase)
Pan paniscus (bonobo/pygmy chimpanzee) : PPOX (protoporphyrinogen oxidase)
Canis lupus familiaris (dog) : PPOX (protoporphyrinogen oxidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppox (protoporphyrinogen oxidase)
Sus scrofa (pig) : PPOX (protoporphyrinogen oxidase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01389,650,094 - 89,654,998 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01394,276,960 - 94,281,296 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,170,602 - 87,174,740 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11387,359,527 - 87,363,605 (-)NCBI
Celera1383,328,348 - 83,332,483 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ppox
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310543
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.