Gene: Eps8 (epidermal growth factor receptor pathway substrate 8) Rattus norvegicus
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Symbol: Eps8
Name: epidermal growth factor receptor pathway substrate 8
Description: Predicted to contribute to Rac guanyl-nucleotide exchange factor activity; predicted to be involved in several processes, including Ras protein signal transduction, actin cytoskeleton organization, and actin polymerization-dependent cell motility; localizes to the glutamatergic synapse and postsynaptic density; orthologous to human EPS8 (epidermal growth factor receptor pathway substrate 8); PARTICIPATES IN platelet-derived growth factor signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,2',4,4'-Tetrabromodiphenyl ether; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: MODEL
Also known as: epidermal growth factor receptor kinase substrate 8; LOC312812
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04171,475,155 - 171,645,620 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04235,732,277 - 235,903,027 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44174,601,291 - 174,672,247 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14174,848,196 - 174,917,371 (-)NCBI
Celera4158,967,950 - 159,084,908 (-)NCBICelera
Cytogenetic Map4q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Eps8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310590
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.