Gene: Itgav (integrin subunit alpha V) Rattus norvegicus
Symbol: Itgav
Name: integrin subunit alpha V
Description: Exhibits signaling receptor binding activity; predicted to contribute to several functions, including C-X3-C chemokine binding activity, growth factor binding activity, and opsonin binding activity; involved in several processes, including blood vessel morphogenesis, cell migration, and positive regulation of cell population proliferation; predicted to localize to several cellular components, including the cell projection membrane, cytosol, and plasma membrane protein complex; used to study corneal neovascularization, coronary stenosis, and ischemia; biomarker of hypertension; orthologous to human ITGAV (integrin subunit alpha V); PARTICIPATES IN integrin mediated signaling pathway; platelet-derived growth factor signaling pathway; sphingosine 1-phosphate signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: MODEL
Also known as: Cd51; Dnmt3l-ps1 pseudogene; integrin alpha V ; integrin alpha-V; integrin, alpha V; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
Homo sapiens (human) : ITGAV (integrin subunit alpha V)  HGNC  Alliance
Mus musculus (house mouse) : Itgav (integrin alpha V)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgav (integrin subunit alpha V)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGAV (integrin subunit alpha V)
Canis lupus familiaris (dog) : ITGAV (integrin subunit alpha V)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgav (integrin subunit alpha V)
Sus scrofa (pig) : ITGAV (integrin subunit alpha V)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0371,113,269 - 71,205,958 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0377,643,270 - 77,731,358 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4366,953,403 - 67,029,774 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1366,848,789 - 66,926,146 (+)NCBI
Celera368,209,136 - 68,297,332 (+)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Itgav
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310613
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.