Gene: Nkx2-8 (NK2 homeobox 8) Rattus norvegicus
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Symbol: Nkx2-8
Name: NK2 homeobox 8
Description: Exhibits sequence-specific DNA binding activity; predicted to be involved in several processes, including axonogenesis, lung development, and negative regulation of epithelial cell proliferation; localizes to the nucleus; orthologous to human NKX2-8 (NK2 homeobox 8); INTERACTS WITH bisphenol A; 17beta-estradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: homeobox protein Nkx-2.8; LOC299061; NK2 transcription factor related, locus 9; NK2 transcription factor related, locus 9 (Drosophila) ; Nkx2-9
Orthologs:
Homo sapiens (human) : NKX2-8 (NK2 homeobox 8)  HGNC  Alliance
Mus musculus (house mouse) : Nkx2-9 (NK2 homeobox 9)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nkx2-8 (NK2 homeobox 8)
Pan paniscus (bonobo/pygmy chimpanzee) : NKX2-8 (NK2 homeobox 8)
Canis lupus familiaris (dog) : NKX2-8 (NK2 homeobox 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nkx2-8 (NK2 homeobox 8)
Sus scrofa (pig) : NKX2-8 (NK2 homeobox 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0677,506,882 - 77,508,585 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0687,033,998 - 87,035,701 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4677,007,954 - 77,009,657 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1677,011,215 - 77,012,752 (-)NCBI
Celera672,893,390 - 72,895,093 (-)NCBICelera
Cytogenetic Map6q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Nkx2-8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310629
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.