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Gene: Diaph1 (diaphanous-related formin 1) Rattus norvegicus
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Symbol: Diaph1
Name: diaphanous-related formin 1
Description: Predicted to have several functions, including identical protein binding activity; ion channel binding activity; and profilin binding activity. Involved in positive regulation of cell migration. Predicted to localize to several cellular components, including the brush border; mitotic spindle; and ruffle membrane. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 1 and sensorineural hearing loss. Orthologous to human DIAPH1 (diaphanous related formin 1); PARTICIPATES IN E-cadherin signaling pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Diap1; diaphanous homolog 1; diaphanous homolog 1 (Drosophila); DRF1; LOC307483; mDIA1
Orthologs:
Homo sapiens (human) : DIAPH1 (diaphanous related formin 1)  HGNC  Alliance
Mus musculus (house mouse) : Diaph1 (diaphanous related formin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Diaph1 (diaphanous related formin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DIAPH1 (diaphanous related formin 1)
Canis lupus familiaris (dog) : DIAPH1 (diaphanous related formin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Diaph1 (diaphanous related formin 1)
Sus scrofa (pig) : DIAPH1 (diaphanous related formin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01830,972,907 - 31,071,371 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01830,663,859 - 30,762,658 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41830,757,191 - 30,855,548 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11830,784,366 - 30,882,101 (-)NCBI
Celera1829,313,748 - 29,412,995 (-)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Diaph1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310707
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.