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Gene: Diaph1 (diaphanous-related formin 1) Rattus norvegicus
Symbol: Diaph1
Name: diaphanous-related formin 1
CRRD ID: 1310707
Description: Predicted to have several functions, including Rho GTPase binding activity; ion channel binding activity; and profilin binding activity. Involved in positive regulation of cell migration. Predicted to colocalize with spindle microtubule. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 1 and sensorineural hearing loss. Orthologous to human DIAPH1 (diaphanous related formin 1); PARTICIPATES IN E-cadherin signaling pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Diap1; diaphanous homolog 1; diaphanous homolog 1 (Drosophila); DRF1; LOC307483; mDIA1
Homo sapiens (human) : DIAPH1 (diaphanous related formin 1)  HGNC  Alliance
Mus musculus (house mouse) : Diaph1 (diaphanous related formin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Diaph1 (diaphanous related formin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DIAPH1 (diaphanous related formin 1)
Canis lupus familiaris (dog) : DIAPH1 (diaphanous related formin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Diaph1 (diaphanous related formin 1)
Sus scrofa (pig) : DIAPH1 (diaphanous related formin 1)
Chlorocebus sabaeus (African green monkey) : DIAPH1 (diaphanous related formin 1)
Heterocephalus glaber (naked mole-rat) : Diaph1 (diaphanous related formin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01830,972,907 - 31,071,371 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1830,972,907 - 31,071,371 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01830,663,859 - 30,762,658 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41830,757,191 - 30,855,548 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11830,784,366 - 30,882,101 (-)NCBI
Celera1829,313,748 - 29,412,995 (-)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Diaph1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310707
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.