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Gene: Nrros (negative regulator of reactive oxygen species) Rattus norvegicus
Symbol: Nrros
Name: negative regulator of reactive oxygen species
CRRD ID: 1310771
Description: Predicted to have transforming growth factor beta binding activity. Predicted to be involved in several processes, including microglia development; sequestering of TGFbeta in extracellular matrix; and transforming growth factor beta1 activation. Predicted to localize to cell surface and endoplasmic reticulum. Orthologous to human NRROS (negative regulator of reactive oxygen species); INTERACTS WITH 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
Also known as: Garpl1; leucine rich repeat containing 33; leucine-rich repeat-containing protein 33; leucine-rich repeat-containing protein 33^; LOC303875; Lrrc33; MGC108848; RGD1310771; similar to GARP protein precursor (Garpin) (Glycoprotein A repetitions predominant); transforming growth factor beta activator LRRC33
Homo sapiens (human) : NRROS (negative regulator of reactive oxygen species)  HGNC  Alliance
Mus musculus (house mouse) : Nrros (negative regulator of reactive oxygen species)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nrros (negative regulator of reactive oxygen species)
Pan paniscus (bonobo/pygmy chimpanzee) : NRROS (negative regulator of reactive oxygen species)
Canis lupus familiaris (dog) : NRROS (negative regulator of reactive oxygen species)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nrros (negative regulator of reactive oxygen species)
Sus scrofa (pig) : NRROS (negative regulator of reactive oxygen species)
Chlorocebus sabaeus (African green monkey) : NRROS (negative regulator of reactive oxygen species)
Heterocephalus glaber (naked mole-rat) : Nrros (negative regulator of reactive oxygen species)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01171,872,728 - 71,889,897 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,872,830 - 71,889,887 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01174,956,672 - 74,973,823 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41170,449,116 - 70,466,412 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11170,506,704 - 70,523,991 (+)NCBI
Celera1168,051,440 - 68,068,647 (+)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Nrros
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310771
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.