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Gene: Nrros (negative regulator of reactive oxygen species) Rattus norvegicus
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Symbol: Nrros
Name: negative regulator of reactive oxygen species
CRRD ID: 1310771
Description: Predicted to have transforming growth factor beta binding activity. Predicted to be involved in several processes, including microglia development; sequestering of TGFbeta in extracellular matrix; and transforming growth factor beta1 activation. Predicted to localize to cell surface and endoplasmic reticulum. Orthologous to human NRROS (negative regulator of reactive oxygen species); INTERACTS WITH 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Garpl1; leucine rich repeat containing 33; leucine-rich repeat-containing protein 33; leucine-rich repeat-containing protein 33^; LOC303875; Lrrc33; MGC108848; RGD1310771; similar to GARP protein precursor (Garpin) (Glycoprotein A repetitions predominant); transforming growth factor beta activator LRRC33
Orthologs:
Homo sapiens (human) : NRROS (negative regulator of reactive oxygen species)  HGNC  Alliance
Mus musculus (house mouse) : Nrros (negative regulator of reactive oxygen species)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nrros (negative regulator of reactive oxygen species)
Pan paniscus (bonobo/pygmy chimpanzee) : NRROS (negative regulator of reactive oxygen species)
Canis lupus familiaris (dog) : NRROS (negative regulator of reactive oxygen species)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nrros (negative regulator of reactive oxygen species)
Sus scrofa (pig) : NRROS (negative regulator of reactive oxygen species)
Chlorocebus sabaeus (African green monkey) : NRROS (negative regulator of reactive oxygen species)
Heterocephalus glaber (naked mole-rat) : Nrros (negative regulator of reactive oxygen species)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01171,872,728 - 71,889,897 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,872,830 - 71,889,887 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01174,956,672 - 74,973,823 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41170,449,116 - 70,466,412 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11170,506,704 - 70,523,991 (+)NCBI
Celera1168,051,440 - 68,068,647 (+)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Nrros
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310771
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.