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Gene: Mllt10 (MLLT10, histone lysine methyltransferase DOT1L cofactor) Rattus norvegicus
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Symbol: Mllt10
Name: MLLT10, histone lysine methyltransferase DOT1L cofactor
Description: Predicted to have histone binding activity and nucleosome binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to localize to the cytosol; nucleoplasm; and protein-containing complex. Human ortholog(s) of this gene implicated in acute monocytic leukemia and acute myeloid leukemia. Orthologous to human MLLT10 (MLLT10 histone lysine methyltransferase DOT1L cofactor); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,3-dinitrobenzene; atrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC361285; myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog; myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog (Drosophila); myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); myeloid/lymphoid or mixed-lineage leukemia translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10; protein AF-10; translocated to, 10
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01784,847,660 - 84,981,134 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01786,574,897 - 86,705,158 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41792,246,466 - 92,389,861 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11792,257,298 - 92,400,692 (+)NCBI
Celera1780,112,286 - 80,232,138 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mllt10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310874
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.