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Gene: Tardbp (TAR DNA binding protein) Rattus norvegicus
Symbol: Tardbp
Name: TAR DNA binding protein
CRRD ID: 1310906
Description: Exhibits RNA binding activity. Involved in positive regulation of insulin secretion and response to endoplasmic reticulum stress. Localizes to cytoplasm and nuclear lumen. Human ortholog(s) of this gene implicated in Parkinson's disease; amyotrophic lateral sclerosis; amyotrophic lateral sclerosis type 10; and motor neuron disease. Orthologous to human TARDBP (TAR DNA binding protein); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC298648; TAR DNA-binding protein 43; Tdp-43
Homo sapiens (human) : TARDBP (TAR DNA binding protein)  HGNC  Alliance
Mus musculus (house mouse) : Tardbp (TAR DNA binding protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tardbp (TAR DNA binding protein)
Pan paniscus (bonobo/pygmy chimpanzee) : TARDBP (TAR DNA binding protein)
Canis lupus familiaris (dog) : TARDBP (TAR DNA binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tardbp (TAR DNA binding protein)
Sus scrofa (pig) : TARDBP (TAR DNA binding protein)
Chlorocebus sabaeus (African green monkey) : TARDBP (TAR DNA binding protein)
Heterocephalus glaber (naked mole-rat) : Tardbp (TAR DNA binding protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05165,432,089 - 165,442,232 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5165,432,095 - 165,442,048 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05169,088,684 - 169,099,216 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45165,698,665 - 165,709,531 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15165,708,851 - 165,719,708 (-)NCBI
Celera5157,327,910 - 157,337,955 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Tardbp
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310906
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.