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Gene: Mylk (myosin light chain kinase) Rattus norvegicus
Symbol: Mylk
Name: myosin light chain kinase
Description: Predicted to have enzyme binding activity and myosin light chain kinase activity. Predicted to be involved in several processes, including aorta smooth muscle tissue morphogenesis; bleb assembly; and cellular response to metal ion. Predicted to localize to several cellular components, including cleavage furrow; lamellipodium; and stress fiber. Human ortholog(s) of this gene implicated in adult respiratory distress syndrome; asthma; and thoracic aortic aneurysm. Orthologous to human MYLK (myosin light chain kinase); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 1,3-dinitrobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC288057; myosin light chain kinase, smooth muscle; myosin, light polypeptide kinase
Homo sapiens (human) : MYLK (myosin light chain kinase)  HGNC  Alliance
Mus musculus (house mouse) : Mylk (myosin, light polypeptide kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mylk (myosin light chain kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : MYLK (myosin light chain kinase)
Canis lupus familiaris (dog) : MYLK (myosin light chain kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mylk (myosin light chain kinase)
Sus scrofa (pig) : MYLK (myosin light chain kinase)
Chlorocebus sabaeus (African green monkey) : MYLK (myosin light chain kinase)
Heterocephalus glaber (naked mole-rat) : Mylk (myosin light chain kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01169,013,060 - 69,260,039 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1169,013,050 - 69,223,158 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01172,103,710 - 72,350,517 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41167,602,540 - 67,848,794 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11167,661,997 - 67,920,369 (-)NCBI
Celera1165,239,196 - 65,448,599 (-)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Mylk
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310915
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.