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Gene: Nlrp1a (NLR family, pyrin domain containing 1A) Rattus norvegicus
Symbol: Nlrp1a
Name: NLR family, pyrin domain containing 1A
CRRD ID: 1310963
Description: Exhibits scaffold protein binding activity. Predicted to be involved in several processes, including NLRP1 inflammasome complex assembly; positive regulation of macromolecule metabolic process; and response to muramyl dipeptide. Localizes to neuronal cell body and protein-containing complex. Human ortholog(s) of this gene implicated in vitiligo. Orthologous to human NLRP1 (NLR family pyrin domain containing 1); PARTICIPATES IN interleukin-1 signaling pathway; NOD-like receptor signaling pathway; INTERACTS WITH acetamide; bisphenol A; diazinon.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC360557; NACHT, leucine rich repeat and PYD containing 1; NACHT, LRR and PYD domains-containing protein 1; Nalp1; NLR family protein 1; NLR family, pyrin domain containing 1; Nlrp1; resistant anthrax lethal toxin
Homo sapiens (human) : NLRP1 (NLR family pyrin domain containing 1)  HGNC  Alliance
Mus musculus (house mouse) : Nlrp1a (NLR family, pyrin domain containing 1A)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : NLRP1 (NLR family pyrin domain containing 1)
Canis lupus familiaris (dog) : NLRP1 (NLR family pyrin domain containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nlrp1 (NLR family pyrin domain containing 1)
Sus scrofa (pig) : NLRP1 (NLR family pyrin domain containing 1)
Chlorocebus sabaeus (African green monkey) : NLRP1 (NLR family pyrin domain containing 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01057,692,474 - 57,747,608 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1057,692,474 - 57,822,498 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01057,437,815 - 57,492,207 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41057,963,708 - 58,007,925 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11057,960,835 - 58,122,088 (-)NCBI
Celera1054,924,259 - 54,970,955 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Nlrp1a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310963
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.