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Gene: Gmds (GDP-mannose 4, 6-dehydratase) Rattus norvegicus
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Symbol: Gmds
Name: GDP-mannose 4, 6-dehydratase
Description: Predicted to have GDP-mannose 4,6-dehydratase activity; NADP+ binding activity; and identical protein binding activity. Predicted to be involved in 'de novo' GDP-L-fucose biosynthetic process; GDP-mannose metabolic process; and Notch signaling pathway. Predicted to localize to the cytoplasm. Human ortholog(s) of this gene implicated in open-angle glaucoma. Orthologous to human GMDS (GDP-mannose 4,6-dehydratase); PARTICIPATES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; beta-naphthoflavone.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GDP-mannose 4,6 dehydratase; GDP-mannose 4,6-dehydratase; LOC291095; MGC125154
Orthologs:
Homo sapiens (human) : GMDS (GDP-mannose 4,6-dehydratase)  HGNC  Alliance
Mus musculus (house mouse) : Gmds (GDP-mannose 4, 6-dehydratase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gmds (GDP-mannose 4,6-dehydratase)
Pan paniscus (bonobo/pygmy chimpanzee) : GMDS (GDP-mannose 4,6-dehydratase)
Canis lupus familiaris (dog) : GMDS (GDP-mannose 4,6-dehydratase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gmds (GDP-mannose 4,6-dehydratase)
Sus scrofa (pig) : GMDS (GDP-mannose 4,6-dehydratase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01733,408,722 - 33,938,086 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01735,298,853 - 35,824,292 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41738,461,733 - 39,016,771 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1731,657,264 - 32,181,220 (+)NCBICelera
Cytogenetic Map17p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Gmds
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311008
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.