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Gene: Tbx2 (T-box transcription factor 2) Rattus norvegicus
Symbol: Tbx2
Name: T-box transcription factor 2
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II activating transcription factor binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including circulatory system development; negative regulation of animal organ morphogenesis; and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus and transcription factor complex. Human ortholog(s) of this gene implicated in vertebral anomalies and variable endocrine and T-cell dysfunction. Orthologous to human TBX2 (T-box transcription factor 2); INTERACTS WITH 1,2-dimethylhydrazine; aldehydo-D-glucose; bis(2-ethylhexyl) phthalate.
Type: protein-coding
Also known as: T-box 2; T-box transcription factor TBX2
Homo sapiens (human) : TBX2 (T-box transcription factor 2)  HGNC  Alliance
Mus musculus (house mouse) : Tbx2 (T-box 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbx2 (T-box transcription factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TBX2 (T-box transcription factor 2)
Canis lupus familiaris (dog) : TBX2 (T-box transcription factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbx2 (T-box transcription factor 2)
Sus scrofa (pig) : TBX2 (T-box transcription factor 2)
Chlorocebus sabaeus (African green monkey) : TBX2 (T-box transcription factor 2)
Heterocephalus glaber (naked mole-rat) : Tbx2 (T-box transcription factor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01073,278,932 - 73,290,764 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1073,279,119 - 73,289,921 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01073,184,210 - 73,193,085 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41074,085,203 - 74,092,988 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11074,096,142 - 74,107,239 (+)NCBI
Celera1069,604,924 - 69,612,748 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Tbx2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311014
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.