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Gene: Dux4 (double homeobox 4) Rattus norvegicus
Symbol: Dux4
Name: double homeobox 4
CRRD ID: 1311053
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including negative regulation of G0 to G1 transition; negative regulation of cell population proliferation; and positive regulation of transcription by RNA polymerase II. Predicted to localize to Golgi apparatus; cytosol; and nucleus. Orthologous to several human genes including DUX4L1 (double homeobox 4 like 1 (pseudogene)); DUX4L2 (double homeobox 4 like 2 (pseudogene)); and DUX4L4 (double homeobox 4 like 4 (pseudogene)); INTERACTS WITH amphetamine; butanal (ortholog); tebuconazole (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: double homeobox B-like; double homeobox B-like 1; double homeobox protein 4C-like; Duxbl; Duxbl1; LOC306226; RGD1311053; similar to double homeobox protein
Homo sapiens (human) : DUX4 (double homeobox 4)  HGNC  Alliance
Mus musculus (house mouse) : Dux (double homeobox)  MGI
Canis lupus familiaris (dog) : LOC491532 (double homeobox protein 4-like protein 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0163,754,968 - 3,766,532 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl163,754,968 - 3,765,917 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0163,720,950 - 3,732,462 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4161,600,636 - 1,606,916 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1161,597,461 - 1,606,066 (+)NCBI
Celera161,534,238 - 1,545,775 (+)NCBICelera
Cytogenetic Map16p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Dux4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311053
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.