Gene: Dux4 (double homeobox 4) Rattus norvegicus
Symbol: Dux4
Name: double homeobox 4
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity; predicted to be involved in several processes, including apoptotic process, negative regulation of G0 to G1 transition, and negative regulation of cell population proliferation; predicted to localize to the cytoplasm and intracellular organelle; orthologous to several human genes including DUX4L2 (double homeobox 4 like 2 (pseudogene)), DUX4L4 (double homeobox 4 like 4 (pseudogene)), and DUX4L9 (double homeobox 4 like 9 (pseudogene)); INTERACTS WITH (RS)-amphetamine; butanal (ortholog); tebuconazole (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: double homeobox B-like; double homeobox B-like 1; double homeobox protein 4C-like; Duxbl; Duxbl1; LOC306226; RGD1311053; similar to double homeobox protein
Homo sapiens (human) : DUX4 (double homeobox 4)  HGNC  Alliance
Mus musculus (house mouse) : Dux (double homeobox)  MGI
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0163,754,968 - 3,766,532 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0163,720,950 - 3,732,462 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4161,600,636 - 1,606,916 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1161,597,461 - 1,606,066 (+)NCBI
Celera161,534,238 - 1,545,775 (+)NCBICelera
Cytogenetic Map16p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Dux4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311053
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.