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Gene: Impdh1 (inosine monophosphate dehydrogenase 1) Rattus norvegicus
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Symbol: Impdh1
Name: inosine monophosphate dehydrogenase 1
Description: Predicted to have DNA binding activity and IMP dehydrogenase activity. Involved in response to cold and retina development in camera-type eye. Predicted to localize to the cytosol and nucleus. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 11; retinitis pigmentosa; and retinitis pigmentosa 10. Orthologous to human IMPDH1 (inosine monophosphate dehydrogenase 1); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; INTERACTS WITH (+)-schisandrin B; (RS)-amphetamine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: IMP (inosine 5'-monophosphate) dehydrogenase 1; IMP (inosine monophosphate) dehydrogenase 1; IMP dehydrogenase 1; IMPD 1; IMPDH 1; inosine 5'-phosphate dehydrogenase 1; inosine-5'-monophosphate dehydrogenase 1; LOC362329
Orthologs:
Homo sapiens (human) : IMPDH1 (inosine monophosphate dehydrogenase 1)  HGNC  Alliance
Mus musculus (house mouse) : Impdh1 (inosine monophosphate dehydrogenase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Impdh1 (inosine monophosphate dehydrogenase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IMPDH1 (inosine monophosphate dehydrogenase 1)
Canis lupus familiaris (dog) : IMPDH1 (inosine monophosphate dehydrogenase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Impdh1 (inosine monophosphate dehydrogenase 1)
Sus scrofa (pig) : IMPDH1 (inosine monophosphate dehydrogenase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0456,478,383 - 56,493,987 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0456,245,545 - 56,261,238 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4456,075,236 - 56,090,775 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1456,328,720 - 56,344,413 (-)NCBI
Celera452,909,914 - 52,925,453 (-)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Impdh1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311108
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.