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Gene: Dsg2 (desmoglein 2) Rattus norvegicus
Symbol: Dsg2
Name: desmoglein 2
CRRD ID: 1311143
Description: Predicted to have calcium ion binding activity and cell adhesion molecule binding activity. Involved in maternal process involved in female pregnancy and response to progesterone. Localizes to apical plasma membrane and lateral plasma membrane. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular dysplasia 10 and dilated cardiomyopathy 1BB. Orthologous to human DSG2 (desmoglein 2); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; INTERACTS WITH bis(2-ethylhexyl) phthalate; bisphenol A; cefaloridine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: desmoglein-2; LOC307562
Homo sapiens (human) : DSG2 (desmoglein 2)  HGNC  Alliance
Mus musculus (house mouse) : Dsg2 (desmoglein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dsg2 (desmoglein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DSG2 (desmoglein 2)
Canis lupus familiaris (dog) : DSG2 (desmoglein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dsg2 (desmoglein 2)
Sus scrofa (pig) : DSG2 (desmoglein 2)
Chlorocebus sabaeus (African green monkey) : DSG2 (desmoglein 2)
Heterocephalus glaber (naked mole-rat) : Dsg2 (desmoglein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01815,579,322 - 15,637,720 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1815,579,315 - 15,637,715 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01815,353,348 - 15,411,825 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41812,306,321 - 12,366,719 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11812,366,920 - 12,391,365 (+)NCBI
Celera1811,860,565 - 11,912,367 (+)NCBICelera
Cytogenetic Map18p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Dsg2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311143
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.