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Gene: Dsg2 (desmoglein 2) Rattus norvegicus
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Symbol: Dsg2
Name: desmoglein 2
Description: Predicted to have calcium ion binding activity and cell adhesion molecule binding activity. Involved in maternal process involved in female pregnancy and response to progesterone. Localizes to the apical plasma membrane and lateral plasma membrane. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular dysplasia 10 and dilated cardiomyopathy 1BB. Orthologous to human DSG2 (desmoglein 2); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; INTERACTS WITH bis(2-ethylhexyl) phthalate; bisphenol A; cefaloridine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: desmoglein-2; LOC307562
Orthologs:
Homo sapiens (human) : DSG2 (desmoglein 2)  HGNC  Alliance
Mus musculus (house mouse) : Dsg2 (desmoglein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dsg2 (desmoglein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DSG2 (desmoglein 2)
Canis lupus familiaris (dog) : DSG2 (desmoglein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dsg2 (desmoglein 2)
Sus scrofa (pig) : DSG2 (desmoglein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01815,579,322 - 15,637,720 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01815,353,348 - 15,411,825 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41812,306,321 - 12,366,719 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11812,366,920 - 12,391,365 (+)NCBI
Celera1811,860,565 - 11,912,367 (+)NCBICelera
Cytogenetic Map18p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Dsg2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311143
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.