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Gene: Zic2 (Zic family member 2) Rattus norvegicus
Symbol: Zic2
Name: Zic family member 2
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin DNA binding activity. Predicted to be involved in several processes, including nervous system development; regulation of transcription, DNA-templated; and visual perception. Predicted to localize to cytoplasm and nuclear body. Human ortholog(s) of this gene implicated in holoprosencephaly and holoprosencephaly 5. Orthologous to human ZIC2 (Zic family member 2); PARTICIPATES IN Hedgehog signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC361096; Zic family member 2 (odd-paired homolog, Drosophila); zinc finger protein of the cerebellum 2; zinc finger protein ZIC 2
Homo sapiens (human) : ZIC2 (Zic family member 2)  HGNC  Alliance
Mus musculus (house mouse) : Zic2 (zinc finger protein of the cerebellum 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zic2 (Zic family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ZIC2 (Zic family member 2)
Canis lupus familiaris (dog) : ZIC2 (Zic family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zic2 (Zic family member 2)
Sus scrofa (pig) : ZIC2 (Zic family member 2)
Chlorocebus sabaeus (African green monkey) : ZIC2 (Zic family member 2)
Heterocephalus glaber (naked mole-rat) : Zic2 (Zic family member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.015108,908,366 - 108,913,812 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15108,908,607 - 108,912,737 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015112,296,472 - 112,301,371 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415107,609,060 - 107,613,169 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.115107,624,839 - 107,629,424 (+)NCBI
Celera1598,350,700 - 98,355,483 (+)NCBICelera
Cytogenetic Map15q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Zic2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311174
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.