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Gene: Tm7sf2 (transmembrane 7 superfamily member 2) Rattus norvegicus
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Symbol: Tm7sf2
Name: transmembrane 7 superfamily member 2
Description: Exhibits delta14-sterol reductase activity. Involved in cholesterol biosynthetic process. Localizes to the endoplasmic reticulum membrane. Orthologous to human TM7SF2 (transmembrane 7 superfamily member 2); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: delta(14)-sterol reductase; LOC293688; MGC108990
Orthologs:
Homo sapiens (human) : TM7SF2 (transmembrane 7 superfamily member 2)  HGNC  Alliance
Mus musculus (house mouse) : Tm7sf2 (transmembrane 7 superfamily member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tm7sf2 (transmembrane 7 superfamily member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TM7SF2 (transmembrane 7 superfamily member 2)
Canis lupus familiaris (dog) : TM7SF2 (transmembrane 7 superfamily member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tm7sf2 (transmembrane 7 superfamily member 2)
Sus scrofa (pig) : TM7SF2 (transmembrane 7 superfamily member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01221,426,017 - 221,430,340 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01228,361,453 - 228,365,776 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41208,700,770 - 208,705,093 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11208,854,222 - 208,858,546 (-)NCBI
Celera1200,889,630 - 200,893,953 (-)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tm7sf2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311205
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.