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Gene: Phpt1 (phosphohistidine phosphatase 1) Rattus norvegicus
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Symbol: Phpt1
Name: phosphohistidine phosphatase 1
CRRD ID: 1311355
Description: Exhibits protein histidine phosphatase activity. Involved in negative regulation of lyase activity; positive regulation of insulin secretion involved in cellular response to glucose stimulus; and protein dephosphorylation. Localizes to cytosol. Orthologous to human PHPT1 (phosphohistidine phosphatase 1); PARTICIPATES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; INTERACTS WITH 17beta-estradiol 3-benzoate; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 14 kDa phosphohistidine phosphatase; LOC296571
Orthologs:
Homo sapiens (human) : PHPT1 (phosphohistidine phosphatase 1)  HGNC  Alliance
Mus musculus (house mouse) : Phpt1 (phosphohistidine phosphatase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Phpt1 (phosphohistidine phosphatase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PHPT1 (phosphohistidine phosphatase 1)
Canis lupus familiaris (dog) : PHPT1 (phosphohistidine phosphatase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Phpt1 (phosphohistidine phosphatase 1)
Chlorocebus sabaeus (African green monkey) : PHPT1 (phosphohistidine phosphatase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.032,797,037 - 2,798,436 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,796,997 - 2,798,470 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.032,778,450 - 2,779,849 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.433,744,947 - 3,746,346 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.133,745,120 - 3,746,334 (-)NCBI
Celera33,217,877 - 3,219,276 (-)NCBICelera
Cytogenetic Map3p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Phpt1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311355
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.