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Gene: Fig4 (FIG4 phosphoinositide 5-phosphatase) Rattus norvegicus
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Symbol: Fig4
Name: FIG4 phosphoinositide 5-phosphatase
Description: Exhibits phosphatidylinositol bisphosphate phosphatase activity; phosphatidylinositol-3-phosphatase activity; and phosphatidylinositol-4-phosphate phosphatase activity. Involved in positive regulation of neuron projection development. Colocalizes with the Golgi apparatus; endoplasmic reticulum; and recycling endosome. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4J; Yunis-Varon syndrome; and amyotrophic lateral sclerosis type 11. Orthologous to human FIG4 (FIG4 phosphoinositide 5-phosphatase); PARTICIPATES IN inositol metabolic pathway; phosphoinositide metabolic pathway; INTERACTS WITH (+)-schisandrin B; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 3',5'-cyclic AMP.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: FIG4 homolog (S. cerevisiae); FIG4 homolog, SAC1 lipid phosphatase domain containing; FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae); Kiaa0274; LOC309855; polyphosphoinositide phosphatase; RGD1311375; Sac domain-containing inositol phosphatase 3; Sac3; similar to RIKEN cDNA A530089I17
Orthologs:
Homo sapiens (human) : FIG4 (FIG4 phosphoinositide 5-phosphatase)  HGNC  Alliance
Mus musculus (house mouse) : Fig4 (FIG4 phosphoinositide 5-phosphatase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fig4 (FIG4 phosphoinositide 5-phosphatase)
Pan paniscus (bonobo/pygmy chimpanzee) : FIG4 (FIG4 phosphoinositide 5-phosphatase)
Canis lupus familiaris (dog) : FIG4 (FIG4 phosphoinositide 5-phosphatase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fig4 (FIG4 phosphoinositide 5-phosphatase)
Sus scrofa (pig) : FIG4 (FIG4 phosphoinositide 5-phosphatase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02045,922,806 - 46,044,754 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02047,625,556 - 47,747,494 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42045,123,352 - 45,248,795 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12045,146,775 - 45,222,780 (-)NCBI
Celera2045,399,685 - 45,522,856 (-)NCBICelera
Cytogenetic Map20q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Fig4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311375
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.