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Gene: Xpo5 (exportin 5) Rattus norvegicus
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Symbol: Xpo5
Name: exportin 5
Description: Predicted to have RNA binding activity; Ran GTPase binding activity; and nuclear export signal receptor activity. Predicted to be involved in nucleocytoplasmic transport; positive regulation of RNA interference; and regulation of protein export from nucleus. Predicted to localize to several cellular components, including the RISC complex; RNA nuclear export complex; and cytosol. Human ortholog(s) of this gene implicated in breast cancer; gastrointestinal system cancer (multiple); lung carcinoma (multiple); multiple myeloma; and premature ovarian failure. Orthologous to human XPO5 (exportin 5); PARTICIPATES IN microRNA pathway; ribosome biogenesis pathway; RNA transport pathway; INTERACTS WITH acrylamide; bisphenol A; dibutyl phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Exp5; exportin-5; LOC363194; RanBp21
Orthologs:
Homo sapiens (human) : XPO5 (exportin 5)  HGNC  Alliance
Mus musculus (house mouse) : Xpo5 (exportin 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xpo5 (exportin 5)
Pan paniscus (bonobo/pygmy chimpanzee) : XPO5 (exportin 5)
Canis lupus familiaris (dog) : XPO5 (exportin 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xpo5 (exportin 5)
Sus scrofa (pig) : XPO5 (exportin 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0917,125,201 - 17,163,170 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0916,021,878 - 16,059,659 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4910,302,751 - 10,341,791 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1910,301,317 - 10,341,202 (-)NCBI
Celera912,487,500 - 12,525,483 (-)NCBICelera
Cytogenetic Map9q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Xpo5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311522
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.