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Gene: Depdc5 (DEP domain containing 5, GATOR1 subcomplex subunit) Rattus norvegicus
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Symbol: Depdc5
Name: DEP domain containing 5, GATOR1 subcomplex subunit
CRRD ID: 1311535
Description: Predicted to contribute to GTPase activator activity. Predicted to be involved in cellular response to amino acid starvation; negative regulation of TORC1 signaling; and regulation of autophagy. Predicted to colocalize with Cul3-RING ubiquitin ligase complex. Human ortholog(s) of this gene implicated in focal epilepsy. Orthologous to human DEPDC5 (DEP domain containing 5, GATOR1 subcomplex subunit); PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DEP domain containing 5; DEP domain-containing protein 5; LOC305464
Orthologs:
Allele / Splice: Depdc5em1Kyo   Depdc5em2Kyo  
Genetic Models: F344-Depdc5em1Kyo+/- F344-Depdc5em2Kyo+/-
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01483,089,000 - 83,219,576 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1483,089,000 - 83,219,464 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01483,775,510 - 83,906,381 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41483,484,354 - 83,614,818 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11483,494,440 - 83,629,671 (-)NCBI
Celera1476,647,953 - 76,778,356 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Depdc5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311535
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-09-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.