 Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,1-dichloroethene | increases expression | ISO | RGD:1323056 | 6480464 | vinylidene chloride results in increased expression of VASP mRNA | CTD | PMID:26682919 | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of VASP mRNA | CTD | PMID:25380136 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:1323056 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of VASP mRNA | CTD | PMID:17942748 | 17beta-estradiol | decreases phosphorylation | EXP | | 6480464 | Estradiol deficiency results in decreased phosphorylation of VASP protein | CTD | PMID:18787021 | 17beta-hydroxy-5alpha-androstan-3-one | multiple interactions | ISO | RGD:1323055 | 6480464 | [Dihydrotestosterone results in increased activity of AR protein mutant form] which results in increased phosphorylation of VASP protein | CTD | PMID:18819937 | 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one | multiple interactions | ISO | RGD:1323055 | 6480464 | 1H-(1 more ... | CTD | PMID:17868048 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1323056 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of VASP mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1323056 | 6480464 | Tetrachlorodibenzodioxin affects the expression of VASP mRNA | CTD | PMID:21570461 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:1323055 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of VASP mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of VASP mRNA | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4, 4'-diaminodiphenylmethane results in increased expression of VASP mRNA | CTD | PMID:25380136 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | RGD:1323055 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of VASP mRNA | CTD | PMID:28628672 | 4-hydroxyphenyl retinamide | increases expression | ISO | RGD:1323056 | 6480464 | Fenretinide results in increased expression of VASP mRNA | CTD | PMID:28973697 | 5-fluorouracil | decreases expression | ISO | RGD:1323056 | 6480464 | Fluorouracil results in decreased expression of VASP protein | CTD | PMID:25936796 | 5-fluorouracil | multiple interactions | ISO | RGD:1323056 | 6480464 | Fluorouracil promotes the reaction [resveratrol results in decreased expression of VASP protein], resveratrol promotes the reaction [Fluorouracil results in decreased expression of VASP protein] | CTD | PMID:25936796 | 8-(4-chlorophenylthio)-cGMP | increases phosphorylation | ISO | RGD:1323055 | 6480464 | 8-((4-chlorophenyl)thio)cyclic-3', 5'-GMP results in increased phosphorylation of VASP protein | CTD | PMID:16166323 | 8-(4-chlorophenylthio)-cGMP | decreases phosphorylation | EXP | | 6480464 | 8-((4-chlorophenyl)thio)cyclic-3', 5'-GMP results in decreased phosphorylation of VASP protein | CTD | PMID:11799084 | 8-(4-chlorophenylthio)-cGMP | increases phosphorylation | EXP | | 6480464 | 8-((4-chlorophenyl)thio)cyclic-3', 5'-GMP results in increased phosphorylation of VASP protein | CTD | PMID:11799084 | acetaldehyde | affects expression | ISO | RGD:1323056 | 6480464 | Acetaldehyde affects the expression of VASP mRNA | CTD | PMID:22634333 | all-trans-retinoic acid | increases expression | ISO | RGD:1323055 | 6480464 | Tretinoin results in increased expression of VASP mRNA | CTD | PMID:15498508 | antirheumatic drug | decreases expression | ISO | RGD:1323055 | 6480464 | Antirheumatic Agents results in decreased expression of VASP mRNA | CTD | PMID:24449571 | atrazine | increases expression | ISO | RGD:1323055 | 6480464 | Atrazine results in increased expression of VASP mRNA | CTD | PMID:22378314 | benomyl | multiple interactions | EXP | | 6480464 | Benomyl inhibits the reaction [Nitroglycerin results in increased phosphorylation of VASP protein], Benomyl inhibits the reaction [Pentaerythritol Tetranitrate results in increased phosphorylation of VASP protein] | CTD | PMID:15331769 | benzo[a]pyrene | decreases expression | ISO | RGD:1323056 | 6480464 | Benzo(a)pyrene results in decreased expression of VASP mRNA | CTD | PMID:19770486 | benzo[a]pyrene | increases expression | ISO | RGD:1323055 | 6480464 | Benzo(a)pyrene results in increased expression of VASP mRNA | CTD | PMID:26238291 | bis(2-ethylhexyl) phthalate | increases expression | ISO | RGD:1323055 | 6480464 | Diethylhexyl Phthalate results in increased expression of VASP mRNA | CTD | PMID:31163220 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of VASP mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | RGD:1323055 | 6480464 | bisphenol A results in decreased expression of VASP mRNA | CTD | PMID:29275510 | bisphenol A | multiple interactions | ISO | RGD:1323055 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of VASP mRNA | CTD | PMID:28628672 | bortezomib | decreases expression | ISO | RGD:1323055 | 6480464 | Bortezomib results in decreased expression of VASP mRNA | CTD | PMID:20977926 | Brodifacoum | decreases expression | EXP | | 6480464 | bromfenacoum results in decreased expression of VASP protein | CTD | PMID:28903499 | butanal | increases expression | ISO | RGD:1323055 | 6480464 | butyraldehyde results in increased expression of VASP mRNA | CTD | PMID:26079696 | cadmium atom | increases expression | ISO | RGD:1323055 | 6480464 | Cadmium results in increased expression of VASP mRNA | CTD | PMID:22562489 | carbamazepine | affects expression | ISO | RGD:1323056 | 6480464 | Carbamazepine affects the expression of VASP mRNA | CTD | PMID:22634333 | carbon monoxide | decreases phosphorylation | ISO | RGD:1323056 | 6480464 | Carbon Monoxide results in decreased phosphorylation of VASP protein | CTD | PMID:26582457 | carbon nanotube | increases expression | ISO | RGD:1323056 | 6480464 | Nanotubes, Carbon analog results in increased expression of VASP mRNA | CTD | PMID:25554681 | choline | multiple interactions | ISO | RGD:1323056 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of VASP gene | CTD | PMID:20938992 | chromium atom | multiple interactions | EXP | | 6480464 | Chromium inhibits the reaction [Sucrose results in decreased phosphorylation of VASP protein] | CTD | PMID:17215582 | clopidogrel | multiple interactions | ISO | RGD:1323055 | 6480464 | CYP2C19 gene affects the reaction [clopidogrel affects the phosphorylation of VASP protein] | CTD | PMID:16772608 | cobalt dichloride | decreases expression | ISO | RGD:1323055 | 6480464 | cobaltous chloride results in decreased expression of VASP mRNA | CTD | PMID:19320972 | Colforsin dapropate hydrochloride | increases phosphorylation | ISO | RGD:1323056 | 6480464 | Colforsin results in increased phosphorylation of VASP protein | CTD | PMID:18182247 | copper(II) sulfate | increases expression | ISO | RGD:1323055 | 6480464 | Copper Sulfate results in increased expression of VASP mRNA | CTD | PMID:19549813 | curcumin | increases expression | ISO | RGD:1323055 | 6480464 | Curcumin results in increased expression of VASP mRNA | CTD | PMID:17198877 | cycloheximide | multiple interactions | ISO | RGD:1323056 | 6480464 | VASP mutant form promotes the reaction [[TNF co-treated with Cycloheximide] results in increased cleavage of SPTAN1 protein] | CTD | PMID:18182247 | cyclosporin A | increases expression | ISO | RGD:1323055 | 6480464 | Cyclosporine results in increased expression of VASP mRNA | CTD | PMID:25562108 | cyclosporin A | decreases expression | ISO | RGD:1323055 | 6480464 | Cyclosporine results in decreased expression of VASP mRNA | CTD | PMID:27989131 | cyproconazole | decreases expression | ISO | RGD:1323056 | 6480464 | cyproconazole results in decreased expression of VASP mRNA | CTD | PMID:22045034 | DDE | multiple interactions | ISO | RGD:1323055 | 6480464 | [Dichlorodiphenyl Dichloroethylene results in increased activity of AR protein mutant form] which results in increased phosphorylation of VASP protein | CTD | PMID:18819937 | dexamethasone | decreases expression | EXP | | 6480464 | Dexamethasone results in decreased expression of VASP mRNA | CTD | PMID:20032058 | dexamethasone | multiple interactions | ISO | RGD:1323055 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of VASP mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of VASP mRNA | CTD | PMID:28628672 | dexamethasone | multiple interactions | EXP | | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of VASP mRNA] | CTD | PMID:20032058 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of VASP mRNA | CTD | PMID:21266533 | dibutyl phthalate | increases expression | ISO | RGD:1323056 | 6480464 | Dibutyl Phthalate results in increased expression of VASP mRNA | CTD | PMID:17361019, PMID:21266533 | dioxygen | affects localization | ISO | RGD:1323056 | 6480464 | Oxygen deficiency affects the localization of VASP protein | CTD | PMID:20164382 | doxorubicin | decreases expression | ISO | RGD:1323055 | 6480464 | Doxorubicin results in decreased expression of VASP mRNA | CTD | PMID:29803840 | ethanol | multiple interactions | ISO | RGD:1323055 | 6480464 | [[Gasoline co-treated with Ethanol] results in increased chemical synthesis of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of VASP mRNA | CTD | PMID:29432896 | flusilazole | affects expression | ISO | RGD:1323056 | 6480464 | flusilazole affects the expression of VASP mRNA | CTD | PMID:22634333 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of VASP mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | RGD:1323056 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of VASP gene | CTD | PMID:20938992 | genistein | decreases expression | ISO | RGD:1323055 | 6480464 | Genistein results in decreased expression of VASP mRNA | CTD | PMID:22228119 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of VASP mRNA | CTD | PMID:22061828 | hemin | multiple interactions | EXP | | 6480464 | Hemin inhibits the reaction [Nitroglycerin results in decreased phosphorylation of VASP protein] | CTD | PMID:17541025 | indometacin | multiple interactions | ISO | RGD:1323055 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of VASP mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of VASP mRNA | CTD | PMID:28628672 | isoprenaline | decreases expression | EXP | | 6480464 | Isoproterenol results in decreased expression of VASP protein | CTD | PMID:27890915 | isoprenaline | multiple interactions | EXP | | 6480464 | natakalim inhibits the reaction [Isoproterenol results in decreased expression of VASP protein] | CTD | PMID:27890915 | L-methionine | multiple interactions | ISO | RGD:1323056 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of VASP gene | CTD | PMID:20938992 | lead diacetate | decreases expression | ISO | RGD:1323056 | 6480464 | lead acetate results in decreased expression of VASP mRNA | CTD | PMID:21829687 | mercury atom | decreases expression | ISO | RGD:1323056 | 6480464 | Mercury analog results in decreased expression of VASP mRNA | CTD | PMID:25056781 | mercury(0) | decreases expression | ISO | RGD:1323056 | 6480464 | Mercury analog results in decreased expression of VASP mRNA | CTD | PMID:25056781 | methylmercury chloride | affects expression | ISO | RGD:1323056 | 6480464 | methylmercuric chloride affects the expression of VASP mRNA | CTD | PMID:21613230 | microcystin-LR | increases phosphorylation | ISO | RGD:1323055 | 6480464 | cyanoginosin LR results in increased phosphorylation of VASP protein | CTD | PMID:24677693 more ... | microcystin-LR | multiple interactions | ISO | RGD:1323055 | 6480464 | [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which affects the expression of VASP protein modified form more ... | CTD | PMID:23929704 more ... | N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide | multiple interactions | ISO | RGD:1323055 | 6480464 | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [N(6)-benzoyl-cyclic AMP results in increased phosphorylation of VASP protein] | CTD | PMID:22363678 | N-nitrosodiethylamine | increases expression | ISO | RGD:1323056 | 6480464 | Diethylnitrosamine results in increased expression of VASP mRNA | CTD | PMID:24535843 | N-nitrosodimethylamine | increases expression | EXP | | 6480464 | Dimethylnitrosamine results in increased expression of VASP mRNA | CTD | PMID:25380136 | nebivolol | multiple interactions | EXP | | 6480464 | Nebivolol inhibits the reaction [AGT protein results in decreased expression of VASP protein], Nebivolol inhibits the reaction [Phorbol Esters results in decreased phosphorylation of VASP protein] | CTD | PMID:16940222 | nickel atom | increases expression | ISO | RGD:1323055 | 6480464 | Nickel results in increased expression of VASP mRNA | CTD | PMID:24768652 | nitroglycerin | multiple interactions | ISO | RGD:1323055 | 6480464 | 1H-(1 more ... | CTD | PMID:17868048 | nitroglycerin | increases phosphorylation | ISO | RGD:1323055 | 6480464 | Nitroglycerin results in increased phosphorylation of VASP protein | CTD | PMID:17868048, PMID:20129490 | nitroglycerin | increases phosphorylation | EXP | | 6480464 | Nitroglycerin results in increased phosphorylation of VASP protein | CTD | PMID:14551241, PMID:15331769 | nitroglycerin | decreases phosphorylation | EXP | | 6480464 | Nitroglycerin results in decreased phosphorylation of VASP protein | CTD | PMID:11331261, PMID:17541025 | nitroglycerin | multiple interactions | EXP | | 6480464 | Benomyl inhibits the reaction [Nitroglycerin results in increased phosphorylation of VASP protein], Hemin inhibits the reaction [Nitroglycerin results in decreased phosphorylation of VASP protein] | CTD | PMID:15331769, PMID:17541025 | oxycodone | decreases expression | EXP | | 6480464 | Oxycodone results in decreased expression of VASP mRNA | CTD | PMID:23439660 | paracetamol | affects expression | ISO | RGD:1323056 | 6480464 | Acetaminophen affects the expression of VASP mRNA | CTD | PMID:17562736 | paraquat | decreases expression | ISO | RGD:1323056 | 6480464 | Paraquat results in decreased expression of VASP mRNA | CTD | PMID:12595580 | pentachlorophenol | increases expression | ISO | RGD:1323056 | 6480464 | Pentachlorophenol results in increased expression of VASP mRNA | CTD | PMID:23892564 | pentaerythritol tetranitrate | multiple interactions | EXP | | 6480464 | Benomyl inhibits the reaction [Pentaerythritol Tetranitrate results in increased phosphorylation of VASP protein] | CTD | PMID:15331769 | pentaerythritol tetranitrate | increases phosphorylation | EXP | | 6480464 | Pentaerythritol Tetranitrate results in increased phosphorylation of VASP protein | CTD | PMID:15331769, PMID:17541025 | progesterone | increases expression | ISO | RGD:1323055 | 6480464 | Progesterone results in increased expression of VASP mRNA | CTD | PMID:18497975 | prostaglandin E1 | increases phosphorylation | ISO | RGD:1323055 | 6480464 | Alprostadil results in increased phosphorylation of VASP protein | CTD | PMID:20129490 | prostaglandin E2 | increases phosphorylation | ISO | RGD:1323056 | 6480464 | Dinoprostone results in increased phosphorylation of VASP protein | CTD | PMID:18182247 | resveratrol | multiple interactions | ISO | RGD:1323055 | 6480464 | 1H-(1 more ... | CTD | PMID:17868048 | resveratrol | multiple interactions | ISO | RGD:1323056 | 6480464 | Fluorouracil promotes the reaction [resveratrol results in decreased expression of VASP protein], resveratrol promotes the reaction [Fluorouracil results in decreased expression of VASP protein] | CTD | PMID:25936796 | resveratrol | decreases expression | ISO | RGD:1323056 | 6480464 | resveratrol results in decreased expression of VASP protein | CTD | PMID:25936796 | resveratrol | increases phosphorylation | ISO | RGD:1323055 | 6480464 | resveratrol results in increased phosphorylation of VASP protein | CTD | PMID:17868048, PMID:18716157 | resveratrol | decreases expression | ISO | RGD:1323055 | 6480464 | resveratrol results in decreased expression of VASP protein, resveratrol results in decreased expression of VASP protein modified form | CTD | PMID:18089832, PMID:25550561 | resveratrol | multiple interactions | EXP | | 6480464 | [resveratrol results in increased activity of GSK3B protein] which results in increased phosphorylation of VASP protein | CTD | PMID:19135050 | S-nitroso-N-acetyl-D-penicillamine | increases phosphorylation | EXP | | 6480464 | S-Nitroso-N-Acetylpenicillamine results in increased phosphorylation of VASP protein | CTD | PMID:11799084 | SB 203580 | multiple interactions | ISO | RGD:1323055 | 6480464 | SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of VASP protein] | CTD | PMID:24677693 | simvastatin | decreases phosphorylation | ISO | RGD:1323056 | 6480464 | Simvastatin results in decreased phosphorylation of VASP protein | CTD | PMID:19332549 | sodium arsenite | increases expression | ISO | RGD:1323056 | 6480464 | sodium arsenite results in increased expression of VASP protein | CTD | PMID:29044176 | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of VASP mRNA | CTD | PMID:19281266 | staurosporine | multiple interactions | ISO | RGD:1323056 | 6480464 | VASP mutant form promotes the reaction [Staurosporine promotes the reaction [CASP3 protein results in increased cleavage of SPTAN1 protein]] | CTD | PMID:18182247 | sucrose | multiple interactions | EXP | | 6480464 | Chromium inhibits the reaction [Sucrose results in decreased phosphorylation of VASP protein] | CTD | PMID:17215582 | sucrose | decreases phosphorylation | EXP | | 6480464 | Sucrose results in decreased phosphorylation of VASP protein | CTD | PMID:17215582 | sulindac sulfone | increases phosphorylation | ISO | RGD:1323055 | 6480464 | sulindac sulfone results in increased phosphorylation of VASP protein | CTD | PMID:16166323 | tacrolimus hydrate | decreases expression | ISO | RGD:1323055 | 6480464 | Tacrolimus results in decreased expression of VASP mRNA | CTD | PMID:29380240 | tamibarotene | increases expression | ISO | RGD:1323055 | 6480464 | tamibarotene results in increased expression of VASP mRNA | CTD | PMID:15498508 | testosterone | multiple interactions | EXP | | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of VASP mRNA] | CTD | PMID:20032058 | testosterone enanthate | affects expression | ISO | RGD:1323055 | 6480464 | testosterone enanthate affects the expression of VASP mRNA | CTD | PMID:17440010 | tetrachloromethane | increases expression | ISO | RGD:1323056 | 6480464 | Carbon Tetrachloride results in increased expression of VASP mRNA | CTD | PMID:27339419 | thimerosal | decreases expression | ISO | RGD:1323055 | 6480464 | Thimerosal results in decreased expression of VASP mRNA | CTD | PMID:27188386 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of VASP mRNA | CTD | PMID:23411599 | valproic acid | affects expression | ISO | RGD:1323056 | 6480464 | Valproic Acid affects the expression of VASP mRNA | CTD | PMID:17292431 | valproic acid | decreases expression | ISO | RGD:1323055 | 6480464 | Valproic Acid results in decreased expression of VASP mRNA | CTD | PMID:29154799 | valproic acid | affects expression | ISO | RGD:1323055 | 6480464 | Valproic Acid affects the expression of VASP mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | RGD:1323055 | 6480464 | Valproic Acid results in increased expression of VASP mRNA | CTD | PMID:23179753 | valproic acid | decreases expression | ISO | RGD:1323056 | 6480464 | Valproic Acid results in decreased expression of VASP mRNA | CTD | PMID:22045034 | valproic acid | increases expression | ISO | RGD:1323056 | 6480464 | Valproic Acid results in increased expression of VASP mRNA | CTD | PMID:21427059 | vancomycin | decreases expression | ISO | RGD:1323056 | 6480464 | Vancomycin results in decreased expression of VASP mRNA | CTD | PMID:18930951 | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of VASP mRNA | CTD | PMID:19015723 | vincristine | increases expression | ISO | RGD:1323055 | 6480464 | Vincristine results in increased expression of VASP mRNA | CTD | PMID:23649840 | | |||||||||||||||||||||||
Gene Ontology AnnotationsBiological Process
Cellular Component
Molecular Function
Molecular Pathway Annotations
