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Gene: Sin3a (SIN3 transcription regulator family member A) Rattus norvegicus
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Symbol: Sin3a
Name: SIN3 transcription regulator family member A
Description: Exhibits RNA binding activity. Predicted to contribute to histone deacetylase activity. Involved in several processes, including aging; cellular response to dopamine; and regulation of transcription from RNA polymerase II promoter in response to oxidative stress. Localizes to the chromatin and protein-containing complex. Used to study transient cerebral ischemia. Human ortholog(s) of this gene implicated in chromosome 15q24 deletion syndrome. Orthologous to human SIN3A (SIN3 transcription regulator family member A); PARTICIPATES IN DNA modification pathway; Hedgehog signaling pathway; Huntington's disease pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,4,7,8-Pentachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC363067; paired amphipathic helix protein Sin3a; SIN3 homolog A, transcription regulator; SIN3 homolog A, transcription regulator (yeast); SIN3 transcription regulator homolog A; SIN3 transcription regulator homolog A (yeast); transcriptional regulator, SIN3A; transcriptional regulator, SIN3A (yeast)
Orthologs:
Homo sapiens (human) : SIN3A (SIN3 transcription regulator family member A)  HGNC  Alliance
Mus musculus (house mouse) : Sin3a (transcriptional regulator, SIN3A (yeast))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sin3a (SIN3 transcription regulator family member A)
Pan paniscus (bonobo/pygmy chimpanzee) : SIN3A (SIN3 transcription regulator family member A)
Canis lupus familiaris (dog) : SIN3A (SIN3 transcription regulator family member A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sin3a (SIN3 transcription regulator family member A)
Sus scrofa (pig) : SIN3A (SIN3 transcription regulator family member A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0861,748,590 - 61,803,314 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0860,323,131 - 60,373,454 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4860,832,595 - 60,884,764 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1860,851,648 - 60,904,028 (+)NCBI
Celera856,953,107 - 57,002,726 (+)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Sin3a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311598
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.