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Gene: Sin3a (SIN3 transcription regulator family member A) Rattus norvegicus
Symbol: Sin3a
Name: SIN3 transcription regulator family member A
CRRD ID: 1311598
Description: Exhibits RNA binding activity. Predicted to contribute to histone deacetylase activity. Involved in several processes, including aging; cellular response to dopamine; and regulation of transcription from RNA polymerase II promoter in response to oxidative stress. Localizes to chromatin and protein-containing complex. Used to study transient cerebral ischemia. Human ortholog(s) of this gene implicated in chromosome 15q24 deletion syndrome. Orthologous to human SIN3A (SIN3 transcription regulator family member A); PARTICIPATES IN DNA modification pathway; Hedgehog signaling pathway; Huntington's disease pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,4,7,8-Pentachlorodibenzofuran; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
Also known as: LOC363067; paired amphipathic helix protein Sin3a; SIN3 homolog A, transcription regulator; SIN3 homolog A, transcription regulator (yeast); SIN3 transcription regulator homolog A; SIN3 transcription regulator homolog A (yeast); transcriptional regulator, SIN3A; transcriptional regulator, SIN3A (yeast)
Homo sapiens (human) : SIN3A (SIN3 transcription regulator family member A)  HGNC  Alliance
Mus musculus (house mouse) : Sin3a (transcriptional regulator, SIN3A (yeast))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sin3a (SIN3 transcription regulator family member A)
Pan paniscus (bonobo/pygmy chimpanzee) : SIN3A (SIN3 transcription regulator family member A)
Canis lupus familiaris (dog) : SIN3A (SIN3 transcription regulator family member A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sin3a (SIN3 transcription regulator family member A)
Sus scrofa (pig) : SIN3A (SIN3 transcription regulator family member A)
Chlorocebus sabaeus (African green monkey) : SIN3A (SIN3 transcription regulator family member A)
Heterocephalus glaber (naked mole-rat) : Sin3a (SIN3 transcription regulator family member A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0861,748,590 - 61,803,314 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl861,762,768 - 61,803,099 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0860,323,131 - 60,373,454 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4860,832,595 - 60,884,764 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1860,851,648 - 60,904,028 (+)NCBI
Celera856,953,107 - 57,002,726 (+)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Sin3a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311598
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.