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Gene: Tet2 (tet methylcytosine dioxygenase 2) Rattus norvegicus
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Symbol: Tet2
Name: tet methylcytosine dioxygenase 2
Description: Predicted to have ferrous iron binding activity; methylcytosine dioxygenase activity; and zinc ion binding activity. Involved in response to organic cyclic compound. Predicted to localize to the nucleus. Human ortholog(s) of this gene implicated in acute myeloid leukemia; chronic myelomonocytic leukemia; myelodysplastic syndrome; and myeloproliferative neoplasm. Orthologous to human TET2 (tet methylcytosine dioxygenase 2); PARTICIPATES IN DNA modification pathway; INTERACTS WITH acrylamide; bisphenol A; trichloroethene.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC310859; methylcytosine dioxygenase TET2; probable methylcytosine dioxygenase TET2; RGD1311625; similar to KIAA1546 protein; tet oncogene family member 2
Orthologs:
Homo sapiens (human) : TET2 (tet methylcytosine dioxygenase 2)  HGNC  Alliance
Mus musculus (house mouse) : Tet2 (tet methylcytosine dioxygenase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tet2 (tet methylcytosine dioxygenase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TET2 (tet methylcytosine dioxygenase 2)
Canis lupus familiaris (dog) : TET2 (tet methylcytosine dioxygenase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tet2 (tet methylcytosine dioxygenase 2)
Sus scrofa (pig) : TET2 (tet methylcytosine dioxygenase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02238,719,389 - 238,802,975 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02257,252,323 - 257,335,750 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42231,016,023 - 231,039,777 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12231,002,809 - 231,063,981 (-)NCBI
Celera2214,215,516 - 214,299,103 (-)NCBICelera
Cytogenetic Map2q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Tet2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311625
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.