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Gene: Rasgrp2 (RAS guanyl releasing protein 2) Rattus norvegicus
Symbol: Rasgrp2
Name: RAS guanyl releasing protein 2
Description: Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in cellular response to calcium ion and positive regulation of GTPase activity. Predicted to localize to cytosol and plasma membrane. Human ortholog(s) of this gene implicated in platelet-type bleeding disorder 18. Orthologous to human RASGRP2 (RAS guanyl releasing protein 2); PARTICIPATES IN chemokine mediated signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Type: protein-coding
Also known as: calcium and DAG-regulated guanine nucleotide exchange factor I; calDAG-GEFI; LOC361714; RAS guanyl releasing protein 2 (calcium and DAG-regulated); RAS guanyl-releasing protein 2; RAS, guanyl releasing protein 2
Homo sapiens (human) : RASGRP2 (RAS guanyl releasing protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Rasgrp2 (RAS, guanyl releasing protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rasgrp2 (RAS guanyl releasing protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RASGRP2 (RAS guanyl releasing protein 2)
Canis lupus familiaris (dog) : RASGRP2 (RAS guanyl releasing protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rasgrp2 (RAS guanyl releasing protein 2)
Sus scrofa (pig) : RASGRP2 (RAS guanyl releasing protein 2)
Chlorocebus sabaeus (African green monkey) : RASGRP2 (RAS guanyl releasing protein 2)
Heterocephalus glaber (naked mole-rat) : Rasgrp2 (RAS guanyl releasing protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01221,771,238 - 221,788,765 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1221,773,254 - 221,788,765 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01228,759,339 - 228,776,703 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41209,183,700 - 209,199,170 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11209,342,129 - 209,357,590 (+)NCBI
Celera1201,240,896 - 201,256,235 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Rasgrp2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311630
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.