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Gene: Stat2 (signal transducer and activator of transcription 2) Rattus norvegicus
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Symbol: Stat2
Name: signal transducer and activator of transcription 2
Description: Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; identical protein binding activity; and ubiquitin-like protein ligase binding activity. Predicted to be involved in several processes, including defense response to other organism; receptor signaling pathway via JAK-STAT; and regulation of mitochondrial fission. Predicted to localize to the cytosol; nucleus; and plasma membrane. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human STAT2 (signal transducer and activator of transcription 2); PARTICIPATES IN interleukin-27 signaling pathway; Jak-Stat signaling pathway; chemokine mediated signaling pathway; INTERACTS WITH (+)-schisandrin B; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC288774
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.072,691,064 - 2,707,530 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.072,669,952 - 2,685,673 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,564,385 - 1,580,652 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.171,564,384 - 1,580,651 (+)NCBI
Celera7578,845 - 593,799 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Stat2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311649
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.