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Gene: Uba5 (ubiquitin-like modifier activating enzyme 5) Rattus norvegicus
Symbol: Uba5
Name: ubiquitin-like modifier activating enzyme 5
CRRD ID: 1311702
Description: Predicted to have UFM1 activating enzyme activity; protein homodimerization activity; and zinc ion binding activity. Predicted to be involved in several processes, including myeloid cell differentiation; protein K69-linked ufmylation; and reticulophagy. Predicted to localize to cytosol; endoplasmic reticulum membrane; and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 24 and early infantile epileptic encephalopathy 44. Orthologous to human UBA5 (ubiquitin like modifier activating enzyme 5); INTERACTS WITH (+)-schisandrin B; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 17beta-estradiol.
Type: protein-coding
Also known as: LOC300968; MGC105565; Ube1dc1; ubiquitin-activating enzyme 5; ubiquitin-activating enzyme E1 domain-containing protein 1; ubiquitin-activating enzyme E1-domain containing 1; ubiquitin-like modifier-activating enzyme 5; UFM1-activating enzyme
Homo sapiens (human) : UBA5 (ubiquitin like modifier activating enzyme 5)  HGNC  Alliance
Mus musculus (house mouse) : Uba5 (ubiquitin-like modifier activating enzyme 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Uba5 (ubiquitin like modifier activating enzyme 5)
Pan paniscus (bonobo/pygmy chimpanzee) : UBA5 (ubiquitin like modifier activating enzyme 5)
Canis lupus familiaris (dog) : UBA5 (ubiquitin like modifier activating enzyme 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Uba5 (ubiquitin like modifier activating enzyme 5)
Sus scrofa (pig) : UBA5 (ubiquitin like modifier activating enzyme 5)
Chlorocebus sabaeus (African green monkey) : UBA5 (ubiquitin like modifier activating enzyme 5)
Heterocephalus glaber (naked mole-rat) : Uba5 (ubiquitin like modifier activating enzyme 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.08112,578,607 - 112,594,192 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8112,578,590 - 112,594,261 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08111,967,198 - 111,981,855 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48109,109,592 - 109,124,197 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18109,129,046 - 109,143,652 (-)NCBI
Celera8104,030,471 - 104,045,054 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Uba5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311702
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.