 Gene Ontology Annotations | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Cellular Component
Molecular Function
Molecular Pathway Annotations |
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Analyze GeneStrainQTL List |
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Cellular Component
Molecular Function
Molecular Pathway AnnotationsGene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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Molecular Pathway AnnotationsReferences - curated| 1. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | MGD data from the GO Consortium |
| 3. | Pipeline to import KEGG annotations from KEGG into RGD |
| 4. | RGD automated data pipeline |
| 5. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 6. | RGD automated import pipeline for gene-chemical interactions |
References - uncuratedGenomics
Comparative Map Data| Spred3 (Rattus norvegicus - Norway rat) |
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| SPRED3 (Homo sapiens - human) |
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| Spred3 (Mus musculus - house mouse) |
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| Spred3 (Chinchilla lanigera - long-tailed chinchilla) |
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| SPRED3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| SPRED3 (Canis lupus familiaris - dog) |
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| Spred3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| SPRED3 (Sus scrofa - pig) |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| testis | heart | brain | ovary | uterus | skeletal muscle tissue | colon | gastrocnemius | forebrain | hindbrain | lung | spleen | liver | kidney | adrenal gland | thymus | |
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| High | ||||||||||||||||
| Medium | 6 | 4 | 22 | 19 | ||||||||||||
| Low | 16 | 34 | 19 | 15 | 4 | 3 | 1 | 4 | 6 | 11 | 11 | 13 | 35 | 8 | 8 | |
| Below cutoff | 9 | 3 | 6 | 28 |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_001173344 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_008759144 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_008759145 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_008759146 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017589125 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AAHX01004480 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AC118147 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC166515 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473979 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | NM_001173344 ⟹ NP_001166815 | |||||||||||||||||||
| RefSeq Status: | PROVISIONAL | |||||||||||||||||||
| Type: | CODING | |||||||||||||||||||
| Position: |
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| Sequence: |
TGCCACTAAGGAAATTTATGTCCAAGCTCCGCCTTGCTATGTCCAGGCAGCAACTCTTTCTAAGhide sequence |
| RefSeq Acc Id: | XM_008759144 ⟹ XP_008757366 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GGAGCGGGAGCGAACAGGAGGAGGAGGAGGAGGCCGCGTCGCCGCCGCTCGGAGCCCGGCCGGAhide sequence |
| RefSeq Acc Id: | XM_008759145 ⟹ XP_008757367 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
CTACGTTGCTCCTCCTTTTGGGCCTCTTATTTGACCTGCCACTAAGGAAATTTATGTCCAAGCThide sequence |
| RefSeq Acc Id: | XM_008759146 ⟹ XP_008757368 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GGAAGGTGCTGAAAAGGTGGGGATGGCATGAAAAGGTAGATACGAAAAAGGAAGGTGGGCAAGAhide sequence |
| RefSeq Acc Id: | XM_017589125 ⟹ XP_017444614 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
CTACGTTGCTCCTCCTTTTGGGCCTCTTATTTGACCTGCCACTAAGGAAATTTATGTCCAAGCThide sequence |
Protein Sequences| Protein RefSeqs | NP_001166815 | (Get FASTA) | NCBI Sequence Viewer |
| XP_008757366 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_008757367 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_008757368 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017444614 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAI66515 | (Get FASTA) | NCBI Sequence Viewer |
| EDM07847 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM07848 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_001166815 ⟸ NM_001173344 |
| - UniProtKB: | B2GV40 (UniProtKB/TrEMBL) |
| - Sequence: |
MYARLASTPPPSRPLPHTRLPGSPSLPPRPGSRCPSPAPPEPARERERTGGGGGGRVAAARSPAhide sequence |
| RefSeq Acc Id: | XP_008757366 ⟸ XM_008759144 |
| - Peptide Label: | isoform X3 |
| - UniProtKB: | A0A096MJ78 (UniProtKB/TrEMBL) |
| - Sequence: |
MVRVRAVVMARDDSSGGWLPVGGGGLSQVSVCRVRGARPEGGARQGHYVIHGERLRDQKTTLEChide sequence |
| RefSeq Acc Id: | XP_008757367 ⟸ XM_008759145 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MGAIGAVRCSSSRSLGPSGNVRPPCFYPSPKPPPPPHASSRFPLPPPSPRLPVPVSSAAGASQGhide sequence |
| RefSeq Acc Id: | XP_008757368 ⟸ XM_008759146 |
| - Peptide Label: | isoform X3 |
| - UniProtKB: | A0A096MJ78 (UniProtKB/TrEMBL) |
| - Sequence: |
MVRVRAVVMARDDSSGGWLPVGGGGLSQVSVCRVRGARPEGGARQGHYVIHGERLRDQKTTLEChide sequence |
| RefSeq Acc Id: | XP_017444614 ⟸ XM_017589125 |
| - Peptide Label: | isoform X2 |
| - Sequence: |
MGAIGAVRCSSSRSLGPSGNVRPPCFYPSPKPPPPPHASSRFPLPPPSPRLPVPVSSAAGASQGhide sequence |
TranscriptomePromoters| RGD ID: | 13689904 | |||||||||
| Promoter ID: | EPDNEW_R424 | |||||||||
| Type: | single initiation site | |||||||||
| Name: | Spred3_1 | |||||||||
| Description: | sprouty-related, EVH1 domain containing 3 | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | |||||||||
| Experiment Methods: | Single-end sequencing. | |||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1311713 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000051915 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000072614 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOP00000072996 | ENTREZGENE, UniProtKB/TrEMBL | |
| Ensembl Transcript | ENSRNOT00000077195 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOT00000090615 | ENTREZGENE, UniProtKB/TrEMBL | |
| Gene3D-CATH | 2.30.29.30 | UniProtKB/TrEMBL |
| IMAGE_CLONE | IMAGE:7131550 | IMAGE-MGC_LOAD |
| InterPro | EVH1 | UniProtKB/TrEMBL |
| KBD | UniProtKB/TrEMBL | |
| PH_type | UniProtKB/TrEMBL | |
| SPRE_EVH1 | UniProtKB/TrEMBL | |
| Sprouty | UniProtKB/TrEMBL | |
| KEGG Report | rno:308478 | UniProtKB/TrEMBL |
| MGC_CLONE | MGC:188090 | IMAGE-MGC_LOAD |
| NCBI Gene | 308478 | ENTREZGENE |
| Pfam | Sprouty | UniProtKB/TrEMBL |
| WH1 | UniProtKB/TrEMBL | |
| PhenoGen | Spred3 | PhenoGen |
| PROSITE | KBD | UniProtKB/TrEMBL |
| SPR | UniProtKB/TrEMBL | |
| WH1 | UniProtKB/TrEMBL | |
| SMART | WH1 | UniProtKB/TrEMBL |
| UniGene | Rn.137062 | ENTREZGENE |
| UniProt | A0A096MJ78 | ENTREZGENE, UniProtKB/TrEMBL |
| A0A0G2K3F4_RAT | UniProtKB/TrEMBL | |
| B2GV40 | ENTREZGENE, UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2008-02-27 | Spred3 | sprouty-related, EVH1 domain containing 3 | RGD1311713_predicted | similar to SPRED-3 (predicted) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2005-01-20 | RGD1311713_predicted | similar to SPRED-3 (predicted) | LOC308478_predicted | Symbol and Name status set to approved | 1331353 | APPROVED | |
| 2005-01-12 | LOC308478_predicted | similar to SPRED-3 (predicted) | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
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| More on Spred3 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| CRRD Object Information | |
| CRRD ID: | 1311713 |
| Created: | 2005-01-12 |
| Species: | Rattus norvegicus |
| Last Modified: | 2019-11-27 |
| Status: | ACTIVE |
