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Gene: Iqgap1 (IQ motif containing GTPase activating protein 1) Rattus norvegicus
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Symbol: Iqgap1
Name: IQ motif containing GTPase activating protein 1
Description: Exhibits mitogen-activated protein kinase binding activity. Involved in several processes, including positive regulation of cellular component organization; positive regulation of protein phosphorylation; and positive regulation of vascular associated smooth muscle cell migration. Localizes to several cellular components, including growth cone; membrane raft; and nucleus. Colocalizes with actin cytoskeleton; focal adhesion; and microtubule cytoskeleton. Orthologous to human IQGAP1 (IQ motif containing GTPase activating protein 1); PARTICIPATES IN E-cadherin signaling pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; platelet-derived growth factor signaling pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1-naphthyl isothiocyanate; 3',5'-cyclic AMP.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC361598; ras GTPase-activating-like protein IQGAP1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01142,525,041 - 142,615,673 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1142,525,046 - 142,615,673 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01143,476,882 - 143,567,395 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41136,552,358 - 136,642,545 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11136,631,848 - 136,722,691 (-)NCBI
Celera1126,734,261 - 126,824,269 (-)NCBICelera
Cytogenetic Map1q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Iqgap1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311884
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.