Gene: Trex1 (three prime repair exonuclease 1) Rattus norvegicus
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Symbol: Trex1
Name: three prime repair exonuclease 1
Description: Predicted to have several functions, including 3'-5'-exodeoxyribonuclease activity, DNA binding activity, and mismatch repair complex binding activity; predicted to be involved in several processes, including DNA metabolic process, animal organ development, and negative regulation of cell cycle; predicted to localize to the cytoplasm, intracellular organelle, and protein-DNA complex; orthologous to human TREX1 (three prime repair exonuclease 1); PARTICIPATES IN DNA replication pathway; G2/M DNA damage checkpoint pathway; INTERACTS WITH (+)-pilocarpine; (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC301014; MGC109019; RGD1309596; three-prime repair exonuclease 1
Orthologs:
Homo sapiens (human) : TREX1 (three prime repair exonuclease 1)  HGNC  Alliance
Mus musculus (house mouse) : Trex1 (three prime repair exonuclease 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trex1 (three prime repair exonuclease 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TREX1 (three prime repair exonuclease 1)
Canis lupus familiaris (dog) : TREX1 (three prime repair exonuclease 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trex1 (three prime repair exonuclease 1)
Sus scrofa (pig) : TREX1 (three prime repair exonuclease 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08117,796,127 - 117,797,427 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08117,147,872 - 117,149,172 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48114,071,508 - 114,072,509 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18114,092,776 - 114,106,801 (-)NCBI
Celera8108,998,058 - 108,999,059 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Trex1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1311998
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.