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Gene: Dyrk2 (dual specificity tyrosine phosphorylation regulated kinase 2) Rattus norvegicus
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Symbol: Dyrk2
Name: dual specificity tyrosine phosphorylation regulated kinase 2
Description: Predicted to have ATP binding activity; metal ion binding activity; and protein kinase activity. Predicted to be involved in several processes, including intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; negative regulation of calcineurin-NFAT signaling cascade; and protein phosphorylation. Predicted to localize to several cellular components, including cytosol; nucleoplasm; and ubiquitin ligase complex. Orthologous to human DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: dual specificity tyrosine-phosphorylation-regulated kinase 2; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2; LOC314862
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0761,785,423 - 61,816,775 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl761,786,309 - 61,798,729 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0761,775,902 - 61,807,168 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4758,114,127 - 58,126,547 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1758,138,697 - 58,149,260 (-)NCBI
Celera751,116,337 - 51,128,757 (-)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Dyrk2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312039
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.