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Gene: Mc1r (melanocortin 1 receptor) Rattus norvegicus
Symbol: Mc1r
Name: melanocortin 1 receptor
Description: Exhibits hormone binding activity and melanocortin receptor activity. Involved in positive regulation of feeding behavior. Predicted to localize to the plasma membrane. Human ortholog(s) of this gene implicated in familial melanoma; major depressive disorder; melanoma; and oculocutaneous albinism type II. Orthologous to human MC1R (melanocortin 1 receptor); PARTICIPATES IN G protein mediated signaling pathway via Galphas family; melanocortin system pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate (ortholog); 1H-indole (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: alpha melanocyte stimulating hormone receptor; LOC292083; melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor); melanocyte-stimulating hormone receptor
Homo sapiens (human) : MC1R (melanocortin 1 receptor)  HGNC  Alliance
Mus musculus (house mouse) : Mc1r (melanocortin 1 receptor)  MGI  Alliance
Canis lupus familiaris (dog) : MC1R (melanocortin 1 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mc1r (melanocortin 1 receptor)
Sus scrofa (pig) : MC1R (melanocortin 1 receptor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01956,215,420 - 56,219,987 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01966,926,656 - 66,929,094 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.11953,743,365 - 53,744,540 (+)NCBI
Celera1950,684,385 - 50,688,952 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Mc1r
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312046
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.