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Gene: Mc1r (melanocortin 1 receptor) Rattus norvegicus
Symbol: Mc1r
Name: melanocortin 1 receptor
CRRD ID: 1312046
Description: Exhibits hormone binding activity and melanocortin receptor activity. Involved in positive regulation of feeding behavior. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in familial melanoma; major depressive disorder; melanoma; and oculocutaneous albinism type II. Orthologous to human MC1R (melanocortin 1 receptor); PARTICIPATES IN G protein mediated signaling pathway via Galphas family; melanocortin system pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate (ortholog); 1H-indole (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: alpha melanocyte stimulating hormone receptor; LOC292083; melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor); melanocyte-stimulating hormone receptor
Homo sapiens (human) : MC1R (melanocortin 1 receptor)  HGNC  Alliance
Mus musculus (house mouse) : Mc1r (melanocortin 1 receptor)  MGI  Alliance
Canis lupus familiaris (dog) : MC1R (melanocortin 1 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mc1r (melanocortin 1 receptor)
Sus scrofa (pig) : MC1R (melanocortin 1 receptor)
Heterocephalus glaber (naked mole-rat) : Mc1r (melanocortin 1 receptor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01956,215,420 - 56,219,987 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01966,926,656 - 66,929,094 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.11953,743,365 - 53,744,540 (+)NCBI
Celera1950,684,385 - 50,688,952 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Mc1r
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312046
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.