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Gene: Dstn (destrin) Mus musculus
Symbol: Dstn
Name: destrin
CRRD ID: 1312066
Description: Exhibits actin filament binding activity. Involved in several processes, including actin filament fragmentation; cytokinesis; and positive regulation of actin filament depolymerization. Localizes to cortical actin cytoskeleton. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human DSTN (destrin, actin depolymerizing factor); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610043P17Rik; actin-depolymerizing factor; AD; ADF; AU042046; co; corn1; corneal disease 1; Dsn; sid; sid 23; sid23p
Homo sapiens (human) : DSTN (destrin, actin depolymerizing factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dstn (destrin, actin depolymerizing factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dstn (destrin, actin depolymerizing factor)
Pan paniscus (bonobo/pygmy chimpanzee) : DSTN (destrin, actin depolymerizing factor)
Canis lupus familiaris (dog) : DSTN (destrin, actin depolymerizing factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dstn (destrin, actin depolymerizing factor)
Sus scrofa (pig) : DSTN (destrin, actin depolymerizing factor)
Chlorocebus sabaeus (African green monkey) : DSTN (destrin, actin depolymerizing factor)
Heterocephalus glaber (naked mole-rat) : Dstn (destrin, actin depolymerizing factor)
more info ...
Related Pseudogenes: Gm8270  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl2143,915,320 - 143,943,324 (+)EnsemblGRCm38mm10GRCm38
GRCm382143,915,331 - 143,943,324 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372143,741,067 - 143,769,060 (+)NCBIGRCm37mm9NCBIm37
MGSCv362143,607,052 - 143,634,765 (+)NCBImm8
Celera2145,097,359 - 145,125,469 (+)NCBICelera
Cytogenetic Map2G1NCBI
cM Map270.89NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Dstn
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312066
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.