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Gene: Mtm1 (X-linked myotubular myopathy gene 1) Mus musculus
Symbol: Mtm1
Name: X-linked myotubular myopathy gene 1
Description: Predicted to have intermediate filament binding activity; phosphatase activity; and phosphatidylinositol binding activity. Involved in several processes, including mitochondrion morphogenesis; negative regulation of cellular catabolic process; and negative regulation of intracellular signal transduction. Localizes to the I band. Used to study centronuclear myopathy. Human ortholog(s) of this gene implicated in centronuclear myopathy X-linked and congenital structural myopathy. Is expressed in trunk unsegmented mesenchyme. Orthologous to human MTM1 (myotubularin 1); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AF073996; KIAA4176; mKIAA4176; Mtm; myotubularin; phosphatidylinositol-3,5-bisphosphate 3-phosphatase; phosphatidylinositol-3-phosphate phosphatase
Homo sapiens (human) : MTM1 (myotubularin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mtm1 (myotubularin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mtm1 (myotubularin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MTM1 (myotubularin 1)
Canis lupus familiaris (dog) : MTM1 (myotubularin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mtm1 (myotubularin 1)
Sus scrofa (pig) : MTM1 (myotubularin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38X71,210,767 - 71,315,413 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X68,463,942 - 68,568,470 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X67,475,638 - 67,575,821 (+)NCBImm8
CeleraX62,185,213 - 62,295,121 (+)NCBICelera
Cytogenetic MapX A7.3NCBI
cM MapX36.55NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Mtm1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312104
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.