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Gene: PAPPA2 (pappalysin 2) Homo sapiens
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Symbol: PAPPA2
Name: pappalysin 2
Description: Exhibits metallopeptidase activity. Involved in proteolysis. Localizes to the extracellular exosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: PAPP-A2; PAPP-E; pappalysin-2; PAPPE; PLAC3; placenta-specific 3; pregnancy-associated plasma preproprotein-A2; pregnancy-associated plasma protein A2; pregnancy-associated plasma protein E1; pregnancy-associated plasma protein-E
Orthologs:
Mus musculus (house mouse) : Pappa2 (pappalysin 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pappa2 (pappalysin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pappa2 (pappalysin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PAPPA2 (pappalysin 2)
Canis lupus familiaris (dog) : PAPPA2 (pappalysin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pappa2 (pappalysin 2)
Sus scrofa (pig) : PAPPA2 (pappalysin 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1176,463,171 - 176,845,601 (+)Ensembl
GRCh381176,463,159 - 176,845,601 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371176,432,307 - 176,814,737 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361174,698,930 - 175,078,595 (+)NCBINCBI36hg18NCBI36
Build 341173,163,963 - 173,391,617NCBI
Celera1149,542,925 - 149,922,011 (+)NCBI
Cytogenetic Map1q25.2NCBI
HuRef1147,658,586 - 148,038,306 (+)NCBIHuRef
CHM1_11177,856,925 - 178,236,093 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PAPPA2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312133
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.