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Gene: RASGRP3 (RAS guanyl releasing protein 3) Homo sapiens
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Symbol: RASGRP3
Name: RAS guanyl releasing protein 3
Description: Exhibits GTPase activator activity. Predicted to be involved in MAPK cascade and small GTPase mediated signal transduction. Predicted to localize to the plasma membrane. Implicated in hypertension.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: calcium and DAG-regulated guanine nucleotide exchange factor III; calcium- and diacylglycerol-regulated guanine nucleotide exchange factor III; CalDAG-GEFIII; GRP3; guanine nucleotide exchange factor for Rap1; KIAA0846; RAS guanyl releasing protein 3 (calcium and DAG-regulated); ras guanyl-releasing protein 3
Orthologs:
Mus musculus (house mouse) : Rasgrp3 (RAS, guanyl releasing protein 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rasgrp3 (RAS guanyl releasing protein 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rasgrp3 (RAS guanyl releasing protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : RASGRP3 (RAS guanyl releasing protein 3)
Canis lupus familiaris (dog) : RASGRP3 (RAS guanyl releasing protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rasgrp3 (RAS guanyl releasing protein 3)
Sus scrofa (pig) : RASGRP3 (RAS guanyl releasing protein 3)
Chlorocebus sabaeus (African green monkey) : RASGRP3 (RAS guanyl releasing protein 3)
Heterocephalus glaber (naked mole-rat) : Rasgrp3 (RAS guanyl releasing protein 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl233,436,324 - 33,564,750 (+)Ensembl
GRCh38233,436,348 - 33,564,731 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37233,661,416 - 33,789,798 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36233,514,920 - 33,643,162 (+)NCBINCBI36hg18NCBI36
Celera233,500,106 - 33,628,502 (+)NCBI
Cytogenetic Map2p22.3NCBI
HuRef233,395,400 - 33,523,736 (+)NCBIHuRef
CHM1_1233,590,740 - 33,719,120 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RASGRP3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312152
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.