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Gene: NOP2 (NOP2 nucleolar protein) Homo sapiens
Symbol: NOP2
Name: NOP2 nucleolar protein
Description: Exhibits RNA binding activity. Involved in positive regulation of cell population proliferation; regulation of signal transduction by p53 class mediator; and ribosomal large subunit assembly. Localizes to the nucleolus; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC117384; MGC149287; MGC149288; NOL1; NOL1/NOP2/Sun domain family, member 1; NOP120; NOP2 nucleolar protein homolog; NOP2/Sun domain family, member 1; NSUN1; nucleolar protein 1, 120kDa; nucleolar protein 2 homolog; p120; probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase; proliferating-cell nucleolar antigen p120; proliferation-associated nucleolar protein p120; putative ribosomal RNA methyltransferase NOP2
Mus musculus (house mouse) : Nop2 (NOP2 nucleolar protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nop2 (NOP2 nucleolar protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nop2 (NOP2 nucleolar protein)
Pan paniscus (bonobo/pygmy chimpanzee) : NOP2 (NOP2 nucleolar protein)
Canis lupus familiaris (dog) : NOP2 (NOP2 nucleolar protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nop2 (NOP2 nucleolar protein)
Sus scrofa (pig) : NOP2 (NOP2 nucleolar protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38126,556,871 - 6,568,291 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37126,666,036 - 6,677,498 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,536,298 - 6,547,741 (-)NCBINCBI36hg18NCBI36
Build 34126,536,289 - 6,547,345NCBI
Celera128,282,899 - 8,294,342 (-)NCBI
Cytogenetic Map12p13.31NCBI
HuRef126,520,171 - 6,531,576 (-)NCBIHuRef
CHM1_1126,665,044 - 6,676,501 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NOP2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312158
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.