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Gene: NOP2 (NOP2 nucleolar protein) Homo sapiens
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Symbol: NOP2
Name: NOP2 nucleolar protein
Description: Exhibits RNA binding activity. Involved in positive regulation of cell population proliferation; regulation of signal transduction by p53 class mediator; and ribosomal large subunit assembly. Localizes to the nucleolus; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC117384; MGC149287; MGC149288; NOL1; NOL1/NOP2/Sun domain family, member 1; NOP120; NOP2 nucleolar protein homolog; NOP2/Sun domain family, member 1; NSUN1; nucleolar protein 1, 120kDa; nucleolar protein 2 homolog; p120; probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase; proliferating-cell nucleolar antigen p120; proliferation-associated nucleolar protein p120; putative ribosomal RNA methyltransferase NOP2
Orthologs:
Mus musculus (house mouse) : Nop2 (NOP2 nucleolar protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nop2 (NOP2 nucleolar protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nop2 (NOP2 nucleolar protein)
Pan paniscus (bonobo/pygmy chimpanzee) : NOP2 (NOP2 nucleolar protein)
Canis lupus familiaris (dog) : NOP2 (NOP2 nucleolar protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nop2 (NOP2 nucleolar protein)
Sus scrofa (pig) : NOP2 (NOP2 nucleolar protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,556,871 - 6,568,291 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37126,666,036 - 6,677,498 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,536,298 - 6,547,741 (-)NCBINCBI36hg18NCBI36
Build 34126,536,289 - 6,547,345NCBI
Celera128,282,899 - 8,294,342 (-)NCBI
Cytogenetic Map12p13.31NCBI
HuRef126,520,171 - 6,531,576 (-)NCBIHuRef
CHM1_1126,665,044 - 6,676,501 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NOP2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312158
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.