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Gene: Ago1 (argonaute RISC catalytic subunit 1) Mus musculus
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Symbol: Ago1
Name: argonaute RISC catalytic subunit 1
Description: Exhibits RNA polymerase II proximal promoter sequence-specific DNA binding activity and miRNA binding activity. Involved in miRNA metabolic process; positive regulation of NIK/NF-kappaB signaling; and positive regulation of transcription by RNA polymerase II. Localizes to several cellular components, including the P-body; RISC complex; and cytosol. Is expressed in several structures, including 2-cell stage embryo; central nervous system; lung epithelium; sensory organ; and tooth. Orthologous to human AGO1 (argonaute RISC component 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: argonaute 1; argonaute RISC catalytic component 1; argonaute1; eIF-2C 1; eIF2C 1; Eif2c1; eukaryotic translation initiation factor 2C, 1; mAgo1; Piwi/Argonaute family protein meIF2C1; protein argonaute-1
Orthologs:
Homo sapiens (human) : AGO1 (argonaute RISC component 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ago1 (argonaute RISC component 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ago1 (argonaute RISC component 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AGO1 (argonaute RISC component 1)
Canis lupus familiaris (dog) : AGO1 (argonaute RISC component 1)
Sus scrofa (pig) : AGO1 (argonaute RISC component 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm384126,435,012 - 126,468,709 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374126,112,256 - 126,145,665 (-)NCBIGRCm37mm9NCBIm37
MGSCv364125,941,807 - 125,970,725 (-)NCBImm8
Celera4124,771,815 - 124,805,219 (-)NCBICelera
Cytogenetic Map4 D2.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Ago1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312164
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.