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Gene: SNX6 (sorting nexin 6) Homo sapiens
Symbol: SNX6
Name: sorting nexin 6
Description: Exhibits dynactin binding activity and protein homodimerization activity. Involved in several processes, including cellular response to amyloid-beta; negative regulation of transforming growth factor beta receptor signaling pathway; and retrograde transport, endosome to Golgi. Localizes to the endosome; lysosome; and retromer complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC3157; MSTP010; sorting nexin-6; TFAF2; TRAF4-associated factor 2; tumor necrosis factor receptor-associated factor 4(TRAF4)-associated factor 2
Mus musculus (house mouse) : Snx6 (sorting nexin 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Snx6 (sorting nexin 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Snx6 (sorting nexin 6)
Pan paniscus (bonobo/pygmy chimpanzee) : SNX6 (sorting nexin 6)
Canis lupus familiaris (dog) : SNX6 (sorting nexin 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Snx6 (sorting nexin 6)
Sus scrofa (pig) : SNX6 (sorting nexin 6)
more info ...
Related Pseudogenes: SNX6P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1434,561,093 - 34,630,160 (-)Ensembl
GRCh381434,561,093 - 34,630,148 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371435,030,615 - 35,099,366 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361434,100,369 - 34,169,117 (-)NCBINCBI36hg18NCBI36
Build 341434,100,366 - 34,169,088NCBI
Celera1414,894,794 - 14,963,537 (-)NCBI
Cytogenetic Map14q13.1NCBI
HuRef1415,145,531 - 15,213,532 (-)NCBIHuRef
CHM1_11435,029,388 - 35,098,166 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SNX6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312208
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.