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Gene: MAD1L1 (mitotic arrest deficient 1 like 1) Homo sapiens
Symbol: MAD1L1
Name: mitotic arrest deficient 1 like 1
Description: Exhibits identical protein binding activity and kinetochore binding activity. Involved in mitotic spindle assembly checkpoint and regulation of metaphase plate congression. Localizes to the kinetochore; mitotic spindle; and nuclear pore nuclear basket. Colocalizes with the mitotic spindle pole and nuclear envelope. Implicated in lymphoma and prostate cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: hMAD1; HsMAD1; MAD1; MAD1 mitotic arrest deficient like 1; MAD1 mitotic arrest deficient-like 1; MAD1 mitotic arrest deficient-like 1 (yeast); MAD1-like protein 1; mitotic arrest deficient 1-like protein 1; mitotic checkpoint MAD1 protein homolog; mitotic spindle assembly checkpoint protein MAD1; mitotic-arrest deficient 1, yeast, homolog-like 1; PIG9; tax-binding protein 181; TP53I9; tumor protein p53 inducible protein 9; TXBP181
Mus musculus (house mouse) : Mad1l1 (MAD1 mitotic arrest deficient 1-like 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mad1l1 (mitotic arrest deficient 1 like 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mad1l1 (mitotic arrest deficient 1 like 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MAD1L1 (mitotic arrest deficient 1 like 1)
Canis lupus familiaris (dog) : MAD1L1 (mitotic arrest deficient 1 like 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mad1l1 (mitotic arrest deficient 1 like 1)
Sus scrofa (pig) : MAD1L1 (mitotic arrest deficient 1 like 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3871,815,795 - 2,232,945 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3771,855,428 - 2,272,583 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3671,821,954 - 2,239,109 (-)NCBINCBI36hg18NCBI36
Build 3471,628,673 - 2,043,593NCBI
Celera71,824,029 - 2,242,272 (-)NCBI
Cytogenetic Map7p22.3NCBI
HuRef71,775,090 - 2,191,874 (-)NCBIHuRef
CHM1_171,855,013 - 2,272,150 (-)NCBICHM1_1
CRA_TCAGchr7v271,908,333 - 2,321,257 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MAD1L1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312218
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.