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Gene: Ddr2 (discoidin domain receptor family, member 2) Mus musculus
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Symbol: Ddr2
Name: discoidin domain receptor family, member 2
Description: Exhibits collagen binding activity and protein tyrosine kinase collagen receptor activity. Involved in several processes, including chondrocyte proliferation; collagen fibril organization; and positive regulation of extracellular matrix disassembly. Predicted to localize to several cellular components, including the actin cytoskeleton; apical plasma membrane; and integral component of plasma membrane. Is expressed in alimentary system; central nervous system; genitourinary system; and retina. Orthologous to human DDR2 (discoidin domain receptor tyrosine kinase 2); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW495251; CD167 antigen-like family member B; discoidin domain receptor 2; discoidin domain-containing receptor 2; neurotrophic tyrosine kinase, receptor-related 3; Ntrkr3; receptor protein-tyrosine kinase TKT; tyro10; tyrosine-protein kinase TYRO10
Orthologs:
Homo sapiens (human) : DDR2 (discoidin domain receptor tyrosine kinase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ddr2 (discoidin domain receptor tyrosine kinase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddr2 (discoidin domain receptor tyrosine kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DDR2 (discoidin domain receptor tyrosine kinase 2)
Canis lupus familiaris (dog) : DDR2 (discoidin domain receptor tyrosine kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddr2 (discoidin domain receptor tyrosine kinase 2)
Sus scrofa (pig) : DDR2 (discoidin domain receptor tyrosine kinase 2)
Chlorocebus sabaeus (African green monkey) : DDR2 (discoidin domain receptor tyrosine kinase 2)
Heterocephalus glaber (naked mole-rat) : Ddr2 (discoidin domain receptor tyrosine kinase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1169,972,307 - 170,110,762 (-)EnsemblGRCm38mm10GRCm38
GRCm381169,972,307 - 170,110,836 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371171,902,438 - 172,019,075 (-)NCBIGRCm37mm9NCBIm37
MGSCv361171,814,321 - 171,947,234 (-)NCBImm8
Celera1172,414,199 - 172,477,876 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map176.84NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ddr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312255
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.