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Gene: Ddr2 (discoidin domain receptor family, member 2) Mus musculus
Symbol: Ddr2
Name: discoidin domain receptor family, member 2
Description: Exhibits collagen binding activity and protein tyrosine kinase collagen receptor activity. Involved in several processes, including chondrocyte proliferation; collagen fibril organization; and positive regulation of extracellular matrix disassembly. Predicted to localize to several cellular components, including the actin cytoskeleton; apical plasma membrane; and integral component of plasma membrane. Is expressed in alimentary system; central nervous system; genitourinary system; and retina. Orthologous to human DDR2 (discoidin domain receptor tyrosine kinase 2); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW495251; CD167 antigen-like family member B; discoidin domain receptor 2; discoidin domain-containing receptor 2; neurotrophic tyrosine kinase, receptor-related 3; Ntrkr3; receptor protein-tyrosine kinase TKT; tyro10; tyrosine-protein kinase TYRO10
Homo sapiens (human) : DDR2 (discoidin domain receptor tyrosine kinase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ddr2 (discoidin domain receptor tyrosine kinase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddr2 (discoidin domain receptor tyrosine kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DDR2 (discoidin domain receptor tyrosine kinase 2)
Canis lupus familiaris (dog) : DDR2 (discoidin domain receptor tyrosine kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddr2 (discoidin domain receptor tyrosine kinase 2)
Sus scrofa (pig) : DDR2 (discoidin domain receptor tyrosine kinase 2)
Chlorocebus sabaeus (African green monkey) : DDR2 (discoidin domain receptor tyrosine kinase 2)
Heterocephalus glaber (naked mole-rat) : Ddr2 (discoidin domain receptor tyrosine kinase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1169,972,307 - 170,110,762 (-)EnsemblGRCm38mm10GRCm38
GRCm381169,972,307 - 170,110,836 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371171,902,438 - 172,019,075 (-)NCBIGRCm37mm9NCBIm37
MGSCv361171,814,321 - 171,947,234 (-)NCBImm8
Celera1172,414,199 - 172,477,876 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map176.84NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ddr2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312255
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.