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Gene: COA8 (cytochrome c oxidase assembly factor 8) Homo sapiens
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Symbol: COA8
Name: cytochrome c oxidase assembly factor 8
Description: Involved in several processes, including mitochondrial respiratory chain complex IV assembly; positive regulation of cytochrome-c oxidase activity; and protein stabilization. Localizes to the matrix side of mitochondrial inner membrane. Implicated in cytochrome-c oxidase deficiency disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: APOP; APOP1; APOPT1; apoptogenic 1; apoptogenic 1, mitochondrial; apoptogenic protein 1; apoptogenic protein 1, mitochondrial; C14orf153; chromosome 14 open reading frame 153; hypothetical protein LOC84334; MGC2562; UPF0671 protein C14orf153
Orthologs:
Mus musculus (house mouse) : Apopt1 (apoptogenic, mitochondrial 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Coa8 (cytochrome c oxidase assembly factor 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apopt1 (apoptogenic 1, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : APOPT1 (apoptogenic 1, mitochondrial)
Canis lupus familiaris (dog) : COA8 (cytochrome c oxidase assembly factor 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apopt1 (apoptogenic 1, mitochondrial)
Sus scrofa (pig) : APOPT1 (apoptogenic 1, mitochondrial)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814103,562,960 - 103,593,214 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3714104,029,299 - 104,057,236 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614103,099,084 - 103,128,277 (+)NCBINCBI36hg18NCBI36
Build 3414103,099,083 - 103,128,261NCBI
Celera1484,083,545 - 84,111,477 (+)NCBI
Cytogenetic Map14q32.33NCBI
HuRef1484,207,680 - 84,235,763 (+)NCBIHuRef
CHM1_114103,967,488 - 103,996,716 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on COA8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312327
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.