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Gene: ELAC1 (elaC ribonuclease Z 1) Homo sapiens
Symbol: ELAC1
Name: elaC ribonuclease Z 1
Description: Predicted to have 3'-tRNA processing endoribonuclease activity. Predicted to be involved in tRNA 3'-trailer cleavage, endonucleolytic. Localizes to the cytosol and nucleoplasm; PARTICIPATES IN tRNA maturation pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 3-isobutyl-1-methyl-7H-xanthine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D29; deleted in Ma29; elaC homolog 1; elaC homolog protein 1; FLJ59261; ribonuclease Z 1; RNase Z 1; RNaseZ(S); tRNA 3 endonuclease 1; tRNA 3' processing endoribonuclease; tRNA Z (short form); tRNase Z 1; tRNase ZS; zinc phosphodiesterase ELAC protein 1
Mus musculus (house mouse) : Elac1 (elaC ribonuclease Z 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Elac1 (elaC ribonuclease Z 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Elac1 (elaC ribonuclease Z 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ELAC1 (elaC ribonuclease Z 1)
Canis lupus familiaris (dog) : ELAC1 (elaC ribonuclease Z 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Elac1 (elaC ribonuclease Z 1)
Sus scrofa (pig) : ELAC1 (elaC ribonuclease Z 1)
Chlorocebus sabaeus (African green monkey) : ELAC1 (elaC ribonuclease Z 1)
Heterocephalus glaber (naked mole-rat) : Elac1 (elaC ribonuclease Z 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1850,967,991 - 50,988,121 (+)EnsemblGRCh38hg38GRCh38
GRCh381850,968,040 - 50,988,121 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371848,494,387 - 48,514,491 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361846,748,385 - 46,768,488 (+)NCBINCBI36hg18NCBI36
Build 341846,748,384 - 46,768,488NCBI
Celera1845,351,172 - 45,371,275 (+)NCBI
Cytogenetic Map18q21.2NCBI
HuRef1845,349,736 - 45,369,837 (+)NCBIHuRef
CHM1_11848,489,814 - 48,509,914 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ELAC1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312386
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.