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Gene: FBXO42 (F-box protein 42) Homo sapiens
Symbol: FBXO42
Name: F-box protein 42
Description: Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (SKP1A; MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Dec 2010]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: F-box only protein 42; Fbx42; JFK; just one F-box and Kelch domain-containing protein; KIAA1332
Mus musculus (house mouse) : Fbxo42 (F-box protein 42)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fbxo42 (F-box protein 42)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxo42 (F-box protein 42)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXO42 (F-box protein 42)
Canis lupus familiaris (dog) : FBXO42 (F-box protein 42)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxo42 (F-box protein 42)
Sus scrofa (pig) : FBXO42 (F-box protein 42)
Chlorocebus sabaeus (African green monkey) : FBXO42 (F-box protein 42)
Heterocephalus glaber (naked mole-rat) : Fbxo42 (F-box protein 42)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl116,246,840 - 16,352,480 (-)Ensembl
GRCh38116,246,840 - 16,352,480 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37116,573,339 - 16,678,965 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36116,449,146 - 16,551,535 (-)NCBINCBI36hg18NCBI36
Build 34116,321,865 - 16,424,254NCBI
Celera115,056,452 - 15,158,874 (-)NCBI
Cytogenetic Map1p36.13NCBI
HuRef115,093,755 - 15,196,329 (-)NCBIHuRef
CHM1_1116,371,929 - 16,477,661 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on FBXO42
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312431
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.