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Gene: Kdm8 (lysine (K)-specific demethylase 8) Mus musculus
Symbol: Kdm8
Name: lysine (K)-specific demethylase 8
CRRD ID: 1312489
Description: Predicted to have several functions, including histone demethylase activity (H3-K36 specific); methylated histone binding activity; and peptidase activity. Involved in circadian regulation of gene expression and protein destabilization. Predicted to localize to cytosol and nucleoplasm. Is expressed in several structures, including branchial arch; early conceptus; genitourinary system; nervous system; and trachea. Orthologous to human KDM8 (lysine demethylase 8); PARTICIPATES IN histone modification pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; benzalkonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3110005O21Rik; arginyl C3-hydroxylase KDM8; bifunctional peptidase and arginyl-hydroxylase JMJD5; jmjC domain-containing protein 5; Jmjd5; jumonji C domain-containing protein 5; jumonji domain containing 5; jumonji domain-containing protein 5; L-arginine (3R)-hydroxylase KDM8; lysine-specific demethylase 8
Homo sapiens (human) : KDM8 (lysine demethylase 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kdm8 (lysine demethylase 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm8 (lysine demethylase 8)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM8 (lysine demethylase 8)
Canis lupus familiaris (dog) : KDM8 (lysine demethylase 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm8 (lysine demethylase 8)
Sus scrofa (pig) : KDM8 (lysine demethylase 8)
Chlorocebus sabaeus (African green monkey) : KDM8 (lysine demethylase 8)
Heterocephalus glaber (naked mole-rat) : Kdm8 (lysine demethylase 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm397125,043,788 - 125,062,823 (+)NCBI
GRCm387125,444,620 - 125,463,651 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7125,444,676 - 125,462,269 (+)EnsemblGRCm38mm10GRCm38
MGSCv377132,588,190 - 132,605,773 (+)NCBIGRCm37mm9NCBIm37
MGSCv367125,235,824 - 125,253,407 (+)NCBImm8
Celera7125,303,361 - 125,320,954 (+)NCBICelera
Cytogenetic Map7F3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Kdm8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312489
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.