Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Med13 (mediator complex subunit 13) Mus musculus
Symbol: Med13
Name: mediator complex subunit 13
Description: Predicted to have thyroid hormone receptor binding activity and transcription coactivator activity. Involved in cholesterol homeostasis; negative regulation of DNA-binding transcription factor activity; and triglyceride homeostasis. Localizes to mediator complex. Is expressed in several structures, including adrenal gland; alimentary system; genitourinary system; hemolymphoid system gland; and liver. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability. Orthologous to human MED13 (mediator complex subunit 13); PARTICIPATES IN RNA polymerase II transcription pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110067M05Rik; D030023K18; mediator of RNA polymerase II transcription subunit 13; mediator of RNA polymerase II transcription, subunit 13; Thrap1; thyroid hormone receptor associated protein 1; thyroid hormone receptor associated protein, 240 kDa subunit; thyroid hormone receptor-associated protein 1; thyroid hormone receptor-associated protein complex 240 kDa component; Trap240; Zmediator complex subunit 13
Homo sapiens (human) : MED13 (mediator complex subunit 13)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Med13 (mediator complex subunit 13)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Med13 (mediator complex subunit 13)
Pan paniscus (bonobo/pygmy chimpanzee) : MED13 (mediator complex subunit 13)
Canis lupus familiaris (dog) : MED13 (mediator complex subunit 13)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Med13 (mediator complex subunit 13)
Sus scrofa (pig) : MED13 (mediator complex subunit 13)
Chlorocebus sabaeus (African green monkey) : MED13 (mediator complex subunit 13)
Heterocephalus glaber (naked mole-rat) : Med13 (mediator complex subunit 13)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1186,267,033 - 86,357,602 (-)EnsemblGRCm38mm10GRCm38
GRCm381186,267,033 - 86,357,596 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371186,079,217 - 86,171,027 (-)NCBIGRCm37mm9NCBIm37
MGSCv361186,081,910 - 86,173,720 (-)NCBImm8
Celera1195,885,881 - 95,975,700 (-)NCBICelera
Cytogenetic Map11CNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Med13
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312496
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.