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Gene: Hdac2 (histone deacetylase 2) Mus musculus
Symbol: Hdac2
Name: histone deacetylase 2
Description: Exhibits several functions, including DNA binding activity; Krueppel-associated box domain binding activity; and RNA polymerase II transcription corepressor binding activity. Involved in several processes, including animal organ development; histone modification; and regulation of cell development. Localizes to the RNA polymerase II transcription repressor complex; chromosome; and transcription factor complex. Human ortholog(s) of this gene implicated in stomach cancer. Is expressed in several structures, including early conceptus; genitourinary system; intestine; nervous system; and retina. Orthologous to human HDAC2 (histone deacetylase 2); PARTICIPATES IN CHD family mediated chromatin remodeling pathway; Hedgehog signaling pathway; histone modification pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3'-diindolylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D10Wsu179e; HD2; mRPD3; YAF1; YY1 transcription factor-binding protein; Yy1bp
Homo sapiens (human) : HDAC2 (histone deacetylase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hdac2 (histone deacetylase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hdac2 (histone deacetylase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HDAC2 (histone deacetylase 2)
Canis lupus familiaris (dog) : HDAC2 (histone deacetylase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hdac2 (histone deacetylase 2)
Sus scrofa (pig) : HDAC2 (histone deacetylase 2)
Chlorocebus sabaeus (green monkey) : HDAC2 (histone deacetylase 2)
Heterocephalus glaber (naked mole-rat) : Hdac2 (histone deacetylase 2)
more info ...
Related Pseudogenes: Gm8022  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1036,974,544 - 37,001,889 (+)Ensembl
GRCm381036,974,297 - 37,001,889 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371036,694,350 - 36,721,694 (+)NCBIGRCm37mm9NCBIm37
MGSCv361036,663,960 - 36,691,304 (+)NCBImm8
Celera1037,867,952 - 37,895,247 (+)NCBICelera
Cytogenetic Map10 B1NCBI
cM Map1019.44NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hdac2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312510
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.