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Gene: Hdac2 (histone deacetylase 2) Mus musculus
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Symbol: Hdac2
Name: histone deacetylase 2
Description: Exhibits several functions, including DNA binding activity; Krueppel-associated box domain binding activity; and RNA polymerase II transcription corepressor binding activity. Involved in several processes, including animal organ development; histone modification; and regulation of cell development. Localizes to the RNA polymerase II transcription repressor complex; chromosome; and transcription factor complex. Human ortholog(s) of this gene implicated in stomach cancer. Is expressed in several structures, including early conceptus; genitourinary system; intestine; nervous system; and retina. Orthologous to human HDAC2 (histone deacetylase 2); PARTICIPATES IN CHD family mediated chromatin remodeling pathway; Hedgehog signaling pathway; histone modification pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3'-diindolylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D10Wsu179e; HD2; mRPD3; YAF1; YY1 transcription factor-binding protein; Yy1bp
Orthologs:
Homo sapiens (human) : HDAC2 (histone deacetylase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hdac2 (histone deacetylase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hdac2 (histone deacetylase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HDAC2 (histone deacetylase 2)
Canis lupus familiaris (dog) : HDAC2 (histone deacetylase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hdac2 (histone deacetylase 2)
Sus scrofa (pig) : HDAC2 (histone deacetylase 2)
Chlorocebus sabaeus (green monkey) : HDAC2 (histone deacetylase 2)
Heterocephalus glaber (naked mole-rat) : Hdac2 (histone deacetylase 2)
more info ...
Related Pseudogenes: Gm8022  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1036,974,544 - 37,001,889 (+)Ensembl
GRCm381036,974,297 - 37,001,889 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371036,694,350 - 36,721,694 (+)NCBIGRCm37mm9NCBIm37
MGSCv361036,663,960 - 36,691,304 (+)NCBImm8
Celera1037,867,952 - 37,895,247 (+)NCBICelera
Cytogenetic Map10 B1NCBI
cM Map1019.44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hdac2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312510
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.