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Gene: IL21R (interleukin 21 receptor) Homo sapiens
Symbol: IL21R
Name: interleukin 21 receptor
Description: Exhibits cytokine receptor activity. Predicted to be involved in interleukin-21-mediated signaling pathway. Predicted to localize to the plasma membrane. Implicated in several diseases, including B-cell lymphoma (multiple); autoimmune hypersensitivity disease (multiple); human immunodeficiency virus infectious disease; primary immunodeficiency disease (multiple); and vasculitis (multiple). Biomarker of atopic dermatitis; inflammatory bowel disease; and multiple sclerosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD360; IL-21 receptor; IL-21R; IMD56; interleukin-21 receptor; MGC10967; NILR; novel interleukin receptor
Mus musculus (house mouse) : Il21r (interleukin 21 receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il21r (interleukin 21 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il21r (interleukin 21 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : IL21R (interleukin 21 receptor)
Canis lupus familiaris (dog) : IL21R (interleukin 21 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il21r (interleukin 21 receptor)
Sus scrofa (pig) : IL21R (interleukin 21 receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381627,402,162 - 27,452,043 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371627,413,483 - 27,463,363 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361627,321,224 - 27,369,616 (+)NCBINCBI36hg18NCBI36
Build 341627,321,923 - 27,369,616NCBI
Celera1626,190,799 - 26,240,689 (+)NCBI
Cytogenetic Map16p12.1NCBI
HuRef1625,501,903 - 25,551,799 (+)NCBIHuRef
CHM1_11628,425,032 - 28,475,081 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on IL21R
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312687
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.