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Gene: Lpxn (leupaxin) Mus musculus
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Symbol: Lpxn
Name: leupaxin
Description: Exhibits transcription coregulator activity. Involved in negative regulation of B cell receptor signaling pathway and regulation of cell adhesion mediated by integrin. Localizes to the focal adhesion; nucleus; and podosome. Is expressed in bladder; epithelium of pelvic urethra of female; ovary; thymus medullary core; and ureter. Orthologous to human LPXN (leupaxin); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4933402K05Rik; A530083L21Rik; AV278559; LDPL
Orthologs:
Homo sapiens (human) : LPXN (leupaxin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lpxn (leupaxin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lpxn (leupaxin)
Pan paniscus (bonobo/pygmy chimpanzee) : LPXN (leupaxin)
Canis lupus familiaris (dog) : LPXN (leupaxin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lpxn (leupaxin)
Sus scrofa (pig) : LPXN (leupaxin)
Chlorocebus sabaeus (green monkey) : LPXN (leupaxin)
Heterocephalus glaber (naked mole-rat) : Lpxn (leupaxin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1912,796,193 - 12,833,807 (+)Ensembl
GRCm381912,795,887 - 12,833,813 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371912,873,099 - 12,908,298 (+)NCBIGRCm37mm9NCBIm37
MGSCv361912,865,628 - 12,900,827 (+)NCBImm8
Celera1913,465,696 - 13,499,415 (+)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Lpxn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312735
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.