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Gene: SEC63 (SEC63 homolog, protein translocation regulator) Homo sapiens
Symbol: SEC63
Name: SEC63 homolog, protein translocation regulator
Description: Exhibits RNA binding activity. Involved in SRP-dependent cotranslational protein targeting to membrane and posttranslational protein targeting to membrane, translocation. Localizes to the endoplasmic reticulum and membrane. Implicated in polycystic liver disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DNAJC23; ERdj2; PCLD2; PRO2507; SEC63 homolog; SEC63 protein translocation regulator; SEC63-like; SEC63L; translocation protein SEC63 homolog
Mus musculus (house mouse) : Sec63 (SEC63-like (S. cerevisiae))  MGI  Alliance
Rattus norvegicus (Norway rat) : Sec63 (SEC63 homolog, protein translocation regulator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sec63 (SEC63 homolog, protein translocation regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : SEC63 (SEC63 homolog, protein translocation regulator)
Canis lupus familiaris (dog) : SEC63 (SEC63 homolog, protein translocation regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sec63 (SEC63 homolog, protein translocation regulator)
Sus scrofa (pig) : SEC63 (SEC63 homolog, protein translocation regulator)
more info ...
Related Pseudogenes: SEC63P1   SEC63P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh386107,867,756 - 107,958,208 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376108,188,960 - 108,279,482 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366108,298,215 - 108,386,086 (-)NCBINCBI36hg18NCBI36
Build 346108,298,214 - 108,386,086NCBI
Celera6108,935,760 - 109,025,964 (-)NCBI
Cytogenetic Map6q21NCBI
HuRef6105,758,265 - 105,848,248 (-)NCBIHuRef
CHM1_16108,451,504 - 108,542,131 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SEC63
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1312738
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.